Helvetica Chimica Acta p. 450 - 465 (1983)
Update date:2022-08-04
Topics:
Schmidlin, Tibur
Bruckhardt, Peter E.
Waespe-Sarcevic, Nada
Tamm, Christoph
A general scheme for the synthesis of the tetrahydroisoindolinone moiety of naturally occurring cytochalasans and unnatural analogs was developed.The keystep consist of the intermolecular <2+4>cycloaddition of 4-methylsorbinol (7) to an alkylidene malonic
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