
Tetrahedron Letters p. 1185 - 1188 (1985)
Update date:2022-07-30
Topics:
Guindon, Yvan
Yoakim, Christiane
Bernstein, Michael A.
Morton, Howard E.
The synthesis of Ethyl 5(S),6-Epoxy-3(R)-(methoxymethoxy)hexanoate, a key chiral synthon for the β-hydroxy-δ-lactone portion of Mevinolin and Compactin, via a regiospecific ring opening of a tetrahydrofuran derivative by dimethyboron bromide, is described.
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