Journal of the American Chemical Society p. 6668 - 6673 (1985)
Update date:2022-08-04
Topics:
Lewis, Edward S.
McLaughlin, Mark L.
Douglas, Thomas A.
The Marcus equation to methyl transfers is shown to cover reactions of " soft" nucleophiles, although small discrepancies occur.Rates and equilibria are reported for a series of reactions of arylmethylselenides with (p-chlorophenyl)dimethylselenonium ion.Experimental reaction rates between "hard" methylating agents and "soft" nucleophiles show small deviations from the calculated values, mostly but not always in the direction predicted by the HSAB principle.The Marcus equation fails to explain the previously reported "inversion" of reaction rates of 4-nitrothiophenoxide and of 4-nitrophenoxide with methyl iodide and dimethyl sulfate.Identity rates for dimethyl sulfate, methyl methanesulfonate (using 3He), methyl iodide (using 125I), and methyl triflate (using 35S) in sulfolane are reported.
View MoreChangzhou Extraordinary Pharmatech co.,LTD
website:http://www.feifanchem.com
Contact:+86 519 82111935
Address:Chinese Jiangsu Province Changzhou City Jintan District Jincheng Town Miaotou NO4(Pharmaceutical Park)
Yingkou Sanzheng Organic Chemical Co. Ltd.
Contact:+86-417-3638818
Address:25 Gengxinli Village, Daqing Road, Yingkou, Liaoning, China
RongCheng Tianyu Technology Co.,Ltd.
Contact:86-631-7519595
Address:220Ping Donghai Road RongChengCity,ShangDong Province China
Shanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.
Contact:+86-21-51320130-801, 816
Address:Room 601, No. 1011, Halei Road, Zhangjiang High-Tech Park, Pudong, Shanghai
Wuhan Sunrise Pharmaceutical Technology Co., Ltd
Contact:+86-27-83314682
Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
Doi:10.1021/jo01109a024
(1956)Doi:10.1002/hlca.19610440639
(1961)Doi:10.1016/S0040-4039(01)91133-5
(1984)Doi:10.1021/jo00225a081
(1985)Doi:10.1021/jo00357a021
(1986)Doi:10.1016/S0040-4020(01)96635-9
(1985)