Intramolecular hydroamination reactions catalyzed by zirconium complexes bearing bridged bis(phenolato) ligands

Article abstract of DOI:10.1039/c5ra23270h

Zirconium complexes stabilized by piperazidine- and imidazolidine-bridged bis(phenolato) ligands have been synthesized and characterized. Their activities in catalyzing intramolecular hydroamination reactions have been tested and compared, which reveals the significant role that the ancillary ligands play in influencing catalytic activities. Cationic species derived from zirconium dibenzyl complexes showed good activities in catalyzing intramolecular hydroamination reactions of both primary and secondary amines, and afforded the respective N-heterocycles in 85% to 99% yields. Moreover, this catalytic system also catalyzed sequential cyclization of primary aminodienes, and generated bicyclic tertiary amines in 94-99% yields.