Simple, high yield preparation of N-benzylacetamides by Lewis acid-catalysed reaction of benzyl chlorides or benzyl methyl ethers with acetonitrile

Article abstract of DOI:10.1080/00397919308018613

Reaction of either benzyl chlorides or benzyl methyl ethers with hydrated ferric chloride in acetonitrile results in smooth Ritter reaction and formation of N-benzylacetamides in excellent yield.

Full text of DOI:10.1080/00397919308018613

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Synthetic Communications: An
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Simple, High Yield Preparation
of N-Benzylacetamides by Lewis
Acid-Catalyseed Reaction of Benzyl
Chlorides or Benzyl Methyl Ethers
with Acetonitrile
a
a
Mesut Kacan & Alexander McKillop
a
School of Chemical Sciences, University of East Anglia,
Norwich, NR4 7TJ, U.K
Version of record first published: 23 Sep 2006.
To cite this article: Mesut Kacan & Alexander McKillop (1993): Simple, High Yield Preparation
of N-Benzylacetamides by Lewis Acid-Catalyseed Reaction of Benzyl Chlorides or Benzyl
Methyl Ethers with Acetonitrile, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 23:15, 2185-2189
To link to this article: http://dx.doi.org/10.1080/00397919308018613
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