Bioorganic and Medicinal Chemistry Letters p. 1599 - 1600 (1999)
Update date:2022-08-17
Topics:
Beuchet
Dherbomez
Elkiel
Charles
Letourneux
25-aminolanostenol 1 and 25-aminoeholesterol 2 were hemisynthesized from natural sterols and tested in vitro against Candida albicans. The biological activity of compound 1 was rather weak, whereas 2 exhibited in vitro antifungal activity with MIC value of 4 μM.
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