Highly efficient and mild synthesis of nitrones by catalytic oxidation of hydroxylamines with tetra-n-propylammonium perruthenate

Article abstract of DOI:10.1016/S0040-4039(00)78275-X

Oxidation of N,N-disubstituted hydroxylamines by N-methylmorpholine N- oxide (NMO) and catalytic amounts of tetra-n-propylammonium perruthenate (TPAP) at room temperature occurs very rapidly to give the corresponding nitrones, which can be trapped by dipo