A Combined Electrochemical/Enzymatic Method for in Situ Regeneration of NADH Based on Cathodic Reduction of Cyclic Disulfides

DOI: 10.1021/jo00333a044

Source and publish data:

Journal of Organic Chemistry p. 4100 - 4101 (1981)

Update date:2022-08-12

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Authors:

Shaked, Ze'ev

Barber, James J.

Whitesides, George M.

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Article abstract of DOI:10.1021/jo00333a044

NADH can be regenerated in situ from NAD by a process having as first step the electrochemical reduction of the disulfide groups of lipoamide and oxidized dithiothreitol to the corresponding dithiols; the dihydrolipoamide in this mixture reduces NAD to NADH in a reaction catalyzed by lipoamide dehydrogenase.

Full text of DOI:10.1021/jo00333a044

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