Highly effective synthesis of 4-halo-tetrahydropyrans via a highly diastereoselective in situ Prins-type cyclization reaction

DOI: 10.1016/S0040-4039(99)00027-1

Source and publish data:

Tetrahedron Letters p. 1627 - 1630 (1999)

Update date:2022-09-26

Topics:

Authors:

Yang, Jun

Viswanathan, Ganapathy S.

Li, Chao-Jun

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Article abstract of DOI:10.1016/S0040-4039(99)00027-1

The reaction of aldehyde with homoallyl alcohols mediated by indium trichloride generated 4-chlorotetrahydropyrans in high yields and with high stereoselectivity. The same type of compounds can be generated through a single step, multi-component coupling

Full text of DOI:10.1016/S0040-4039(99)00027-1

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