Tetrahedron Letters p. 6859 - 6860 (1989)
Update date:2022-08-16
Topics:
Loffet, A.
Galeotti, N.
Jouin, P.
Castro, B.
Tert-butyl fluorocarbonate (Boc-F) is efficiently used for the synthesis of tert-butyl esters of N-protected amino acids.The reaction proceeds at room temperature and under mild conditions in the presence of triethylamine and 4-dimethylamino-pyridine.
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