Acidic ionic liquid N-methyl 2-pyrrolidonium hydrogen sulfate as an efficient catalyst for the one-pot multicomponent preparation of 3,4,5-substituted furan-2(5H)-ones

Article abstract of DOI:10.1007/s11164-014-1754-y

Abstract We have developed an efficient method for the synthesis of 3,4,5-substituted furan-2(5H)-ones via one-pot, three-component condensation reaction of aldehydes, amines, and dialkyl acetylenedicarboxylates using acidic ionic liquid catalyst (N-methyl 2-pyrrolidonium hydrogen sulfate ([H-NMP]HSO₄)). This reaction benefits from simple, inexpensive, and straightforward procedure, an environmental friendly method, and high yields.