6214-35-3

Basic information

• Product Name: (Z)-(3)-IODOACRYLIC ACID
• Synonyms: (Z)-(3)-IODOACRYLIC ACID;CIS-3-IODOACRYLIC ACID;cis-3-Iodoacrylic acid,98%;(2Z)-3-Iodo-2-propenoic acid;2-Propenoic acid, 3-iodo-, (2Z)-;(Z)-3-iodoprop-2-enoic acid
• CAS NO: 6214-35-3
• Molecular Formula: C₃H₃IO₂
• Molecular Weight: 197.96
• Mol File: 6214-35-3.mol
• Article Data: 31

Chemical Properties

• Melting Point: 65 °C
• Boiling Point: 248.3 °C at 760 mmHg
• Flash Point: 104 °C
• Appearance: White to yellow crystalline powder
• Density: 2.325 g/cm³
• Vapor Pressure: 0.00783mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (Z)-(3)-IODOACRYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(3)-IODOACRYLIC ACID(6214-35-3)
• EPA Substance Registry System: (Z)-(3)-IODOACRYLIC ACID(6214-35-3)

Safety Data

• Hazardous Substances Data: 6214-35-3(Hazardous Substances Data)

Usage

Chemical Properties

White to yellow crystalline powder

Synthesis Reference(s)

Canadian Journal of Chemistry, 72, p. 1816, 1994 DOI: 10.1139/v94-230Tetrahedron Letters, 24, p. 3973, 1983 DOI: 10.1016/S0040-4039(00)88239-8

InChI:InChI=1/C3H3IO2/c4-2-1-3(5)6/h1-2H,(H,5,6)/b2-1-

Upstream product

• 2956-91-4 1,1,3,3-tetraiodo-propan-2-one 
• 471-25-0 Propiolic acid 
• 74-88-4 methyl iodide 
• 6372-02-7 (E)-3-iodoacrylic acid 

Downstream Products

• 6214-23-9 methyl (2Z)-3-iodoprop-2-enoate 
• 6213-88-3 (E)-methyl 3-iodoacrylate 
• 6372-02-7 (E)-3-iodoacrylic acid 
• 29739-67-1 (Z)-penta-2,4-dienoic acid 
• 35304-86-0 (Z)-5-phenyl-2,4-pentadien-4-olide 
• 886-66-8 1,4-diphenyl-1,3-butadiyne 
• 1577-96-4 (Z)-oct-2-enoic acid 
• 1115184-29-6 (5Z)-5-{[1β-1,2-dideoxy-3,5-di-O-(4-toluoyl)-D-ribofuranosyl]-1'-methylene}furan-2(5H)-one 
• 1115184-31-0 C₂₆H₂₄O₇ 
• 1115184-30-9 C₂₆H₂₄O₇ 
• 1115184-28-5 (5Z)-5-{[1α-1,2-dideoxy-3,5-di-O-(4-toluoyl)-D-ribofuranosyl]-1'-methylene}furan-2(5H)-one 
• 1115184-32-1 1,4-bis[1,2-dideoxy-3,5-di-O-(4-toluoyl)-α-D-ribofuranosyl]butadiyne 
• 108-28-1 protoanemonin 

Relevant articles and documents

Diastereoselective scalable synthesis of 2,6-trans-Piperidines using an aza-Michael reaction

Highly efficient substrate and reagent controlled stereoselective synthesis of 2,6-trans-piperidine derivative (1) using an aza-Michael reaction is reported. This method was utilized to synthesize a variety of trans-piperidines on hundred-gram scales.

Revisiting the hydroiodination of propiolic acid

Z-3-iodoacrylic acid Z-1, that formed by reacting propiolic acid 2 with 57% aqueous III at 80-85 °C, was efficiently converted into the isomeric acid E-1 by treatment in the same conditions.

PYRROLO[2,3-D]PYRIMIDIN-2-ONE ANTIMICROBIAL COMPOUNDS

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. In some embodiments, the present disclosure provides pyrrolo[2,3-d]pyrimidin-2-ones useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.

Studies toward the Total Synthesis of the Marine Macrolide Salarin C

A convergent strategy for the synthesis of dideoxysalarin C (3) as a potential intermediate for the total synthesis of the marine macrolide salarin C (1) is described. The macrolactone core of 3 was assembled by Suzuki coupling between alkyl iodide 9 and