Synthesis p. 379 - 381 (1988)
Update date:2022-08-16
Topics:
Ashwood, Michael S.
Bell, Lawrence A.
Houghton, Peter G.
Wright, Stanley H. B.
The 1,4-addition of Grignard reagents to β-nitrostyrene to give 1,1-diaryl-2-nitroethanes and their subsequent conversion via a modified Nef reaction into 1,1-diaryl-2,2-dimethoxyethanes (diarylacetaldehyde dimethyl acetals) is described.The scope of the reaction has been briefly explored and one example demonstrated on a large scale.
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Doi:10.1002/ejoc.202000615
(2020)Doi:10.1016/j.tet.2012.12.043
(2013)Doi:10.1016/0223-5234(92)90098-L
(1992)Doi:10.1021/om4010516
(2014)Doi:10.1021/ja311021u
(2013)Doi:10.1016/S0040-4039(00)92229-9
(1992)
