β-Selective synthesis of 2′-deoxynucleosides by the coupling of 2-deoxy-1-thio-D-threo-pentofuranosides with silylated thymine

DOI: 10.1016/S0040-4039(00)92229-9

Source and publish data:

Tetrahedron Letters p. 2515 - 2516 (1992)

Update date:2022-08-04

Topics:

Authors:

Sugimura, Hideyuki

Sujino, Keiko

Osumi, Kenji

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)92229-9

The coupling of the 3,5-O-isopropylidene derivative of phenyl 2-deoxy-1-thio-D-threo-pentofuranoside with silylated thymine in the presence of N-bromosuccinimide yielded 1-(2-deoxy-β-D-threo-pentofuranosyl)thymine with highly anomeric selectivity.

Full text of DOI:10.1016/S0040-4039(00)92229-9

Products guided by the article

Product name:1-(3,5-O-Benzylidene-2-deoxy-α-D-threo-pentofuranosyl)thymine

Cas No:142405-92-3

R&D Labs maybe for 142405-92-3

Jiangxi Province Bethel Pharmaceutical Co., Ltd.

Contact:+86-795-259 3456 ，+86-15957688008 13566650571

Address:Huangjindui Chemical Park， Shanggao County ，Yichun city，Jiangxi Province
ClickChem Technology Co., Limited

Contact:+86-0310-6519966/0531-52893837

Address:No.750 Shunhua Road, High-Tech Zone, Jinan city, Shandong China
Wuxi Zuping Food Science And Technology Co.,LTD.

Contact:+86-510-87210822

Address:Guanlin town
Zhejiang Sanmei Chemical Industry Co., Ltd

Contact:86-579-87633213

Address:Huchu Industrial Zone, Qingnian Rd., Wuyi County, Zhejiang Prov., China.
Shenyang Xingzhenghe Chemical Co., Ltd.

Contact:024-23509232

Address:No. 33, Naner Road, Heping Dist.

Relevant to this article

Synthesis and biological evaluation of nucleoside analogues than contain silatrane on the basis of the structure of acyclovir (ACV) as novel inhibitors of hepatitis B virus (HBV)

Doi:10.1016/j.bmcl.2012.12.097
(2013)
New acyclic 1,2,4-triazole-based Schiff base hydrazone: Synthesis, characterization, spectrophotometric and computational studies

Doi:10.1016/j.saa.2012.12.033
(2013)
Reduction of 3-nitrophthalic anhydride by SnCl₂ in different alcohols: A simple synthesis of alkyl 1,3-dihydro-3-oxo-2,1-benzisoxazole-4- carboxylates

Doi:10.1016/j.tetlet.2013.01.037
(2013)
Palladium-catalysed vinylation of allylic alcohols with enol triflates. A convenient synthesis of conjugated dienols

Doi:10.1016/S0040-4039(00)79603-1
(1992)
Antimycobacterial activity evaluation, time-kill kinetic and 3D-QSAR study of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives

Doi:10.1016/j.bmcl.2012.12.083
(2013)
Entry to β-alkoxyacrylates via gold-catalyzed intermolecular coupling of alkynoates and allylic ethers

Doi:10.1021/ol4001087
(2013)

Article Doi