Journal of labelled compounds and radiopharmaceuticals p. 915 - 919 (1995)
Update date:2022-08-30
Topics:
Ueyama
Yanagisawa
Tomiyama
2-Propyl-8-oxo-1-[(2'-(1H-tetrazole-5-yl)biphenyl-4-yl) methyl]4,5,6,7-tetrahydrocyclohept imidazole (KT3-671), which has been found to be a potent and selective angiotesin II receptor antagonist, was synthesized in 14C-labelled form by using potassium[14C]-cyanide. [14C](KT3-671) 9 with a specific activity of 1.74GBq/mmol was prepared in four steps in 29.8% overall radiochemical yield from potassium[14C]-cyanide.
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