A Reaction Calorimetric Investigation of the Hydrogenation of a Substituted Pyrazine

Article abstract of DOI:10.1006/jcat.1995.1280

Reaction calorimetry was the primary tool in investigations of the liquid-phase hydrogenation of a substituted pyrazine compound carried out over supported Pd catalysts.In addition to providing information about gas-liquid mass transfer limitations, calorimetric measurements provided a kinetic analysis of how product selectivity in this consecutive reaction network may be tuned by changing reaction conditions.Concentration profiles developed from fitting the heat flow data to a first-order model were compared with analytical measurements of concentration, demonstrating the utility of combining independent measurements of reaction progress as a means of assessing the validity of a kinetic model.