European Journal of Medicinal Chemistry p. 238 - 252 (2019)
Update date:2022-08-30
Topics:
Sang, Zhipei
Wang, Keren
Zhang, Pengfei
Shi, Jian
Liu, Wenmin
Tan, Zhenghuai
A series of novel chalcone derivatives was designed, synthesized and evaluated as multifunctional agents for the treatment of AD. Among of these synthesized compounds, compound TM-2 was a selective BuChE inhibitor (IC50 = 2.6 μM) and selective
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