Haloacetylated Enol Ethers. 9 [18]. Synthesis of 4-Trifluoromethyl-2-methyl[phenyl]pyrimidines and Tetrahydro Derivatives

DOI: 10.1002/jhet.5570350231

Source and publish data:

Journal of Heterocyclic Chemistry p. 451 - 455 (1998)

Update date:2022-08-11

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Authors:

Zanatta, Nilo

Fagundes, Madelon B.

Ellensohn, Ricardo

Marques, Marcelo

Bonacorso, Helio G.

Martins, Marcos A. P.

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Article abstract of DOI:10.1002/jhet.5570350231

The synthesis of 4-trifluoromethyl-2-methyl[phenyl]pyrimidines and the corresponding tetrahydro derivatives from the cyclo-condensation reaction of β-alkoxyvinyl trifluoromethyl ketones 1a-d with acetamidine or benzamidine hydrochloride, is reported. For

Full text of DOI:10.1002/jhet.5570350231

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