Bioorganic and Medicinal Chemistry Letters p. 6525 - 6528 (2007)
Update date:2022-08-11
Topics:
Galatsis, Paul
Yamagata, Koji
Wendt, John A.
Connolly, Cleo J.
Mickelson, John W.
Milbank, Jared B.J.
Bove, Susan E.
Knauer, Christopher S.
Brooker, Rachel M.
Augelli-Szafran, Corinne E.
Schwarz, Roy D.
Kinsora, Jack J.
Kilgore, Kenneth S.
We describe three novel regioisomeric series of aryl naphthyridine analogs, which are potent antagonists of the Class III GPCR mGlu5 receptor. The synthesis and in vitro and in vivo pharmacological activities of these analogs are discussed.
View MoreContact:Tel: +86-25-58353800
Address:23 Lijing Road, Nanjing Hi-Tech Zone, Nanjing, Jiangsu, China, 210061
Zouping Fuhai Technology Development Co., Ltd.
Contact:+0532-86934525 18660293207
Address:jiuhu town industrial park Zouping County,bingzhou Provincejiuhu town industrial park
Shanghai Forever Biotech Co., Ltd.
Contact:+86-21-69734790
Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
Changzhou Ruiping Chemical Co., Ltd
website:http://www.wishchem.com
Contact:+86-519-82324280
Address:No.288-1 Huacheng Road, Jintan
ALPHA PHARMACEUTICAL CO,LTD JIANGSU
Contact:+86-527-84829968,+86-527-84829998
Address:suqian city
Doi:10.1063/1.476152
(1998)Doi:10.1016/0040-6031(90)80015-Q
(1990)Doi:10.1016/0009-2614(92)80104-J
(1992)Doi:10.1021/ja00226a055
(1988)Doi:10.1080/00304949809355330
(1998)Doi:10.1021/ja01985a002
(1905)