Catalytic asymmetric synthesis of polysubstituted cyclohexa-1,3-dienes from β-branched α,β-alkenals

Article abstract of DOI:10.1007/BF01435793

3-Methyl- and 3-phenylbut-2-enal in the presence of (S)-prolinol (0.1 eq.) in benzene or THF react with the acidic monoesters of alkenylidene-, arylmethylidene-, and alkylidenemalonic acids at -10 to +22 °C to give optically active esters of 4,6-disubstit