Journal of Coordination Chemistry p. 3146 - 3157 (2011)
Update date:2022-08-11
Topics:
Chen, Fengying
Jin, Zhenguo
Li, Hengxin
He, Shuiyang
Two complexes, [Cd2(Im)(HL)2(CH3OH) 3(H2O)2] (1) and [Ni(HL)(Im)2(H 2O)] [Ni(H2L)(Im)2(OH)]·4H2O (2) (H3L = N-(2-propionic acid)-salicyloyl hydrazone, Im = imidazole), have been synthesized and characterized by infrared and single-crystal X-ray diffraction. The bioactivity of 1 was studied by the turbidimetry/spectrometry method and DNA-binding properties of 2 were studied. The result showed that the inhibitory rate of 1 was very good and 2 binds to calf-thymus DNA by the groove-binding mode.
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