Tetrahedron Letters p. 8595 - 8597 (1999)
Update date:2022-08-28
Topics:
Ghelfi, Franco
Ghirardini, Gianluca
Libertini, Emanuela
Forti, Luca
Pagnoni, Ugo M.
3-Benzylimino-2-pyrrolidinones can be prepared in good yield by heating 3-chloro-4-chloromethyl-2-pyrrolidinones, benzylamine and NaI in THF at 80°C. An endo-dehydrohalogenation followed by a SN2' substitution on the intermediate allyl chloride
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(1947)
