532-32-1

Usage

InChI:InChI=1/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1

Synthetic route

benzaldehyde (100-52-7) → sodium benzoate (532-32-1)

Conditions	Yield
With tetraphosphonium peroxodiphosphate; water In phosphate buffer pH=4.0 - 10.0; Kinetics; Product distribution; Further Variations:; flash-photolysis; UV-irradiation;	100%
With sodium hydroxide; sodium periodate; ruthenium trichloride In water at 35℃; Kinetics; Mechanism; Thermodynamic data; other temperatures; dependence on the concentrations of substrate, base; ΔE(excit.), ΔH(excit.), ΔS(excit.);

2-Nonylsulfonyl-1-phenyl-1-ethanon (85057-92-7) → sodium benzoate (532-32-1) + 1-(Brommethylsulfonyl)nonan (85057-99-4)

Conditions	Yield
With sodium hydroxide; bromine In ethanol for 12h; Ambient temperature;	A n/a B 98%

benzyl alcohol (100-51-6) → sodium benzoate (532-32-1)

Conditions	Yield
With oxygen; sodium hydroxide In neat (no solvent) at 179.84℃; for 8h; Reagent/catalyst;	92%
With sodium hydroxide; palladium on activated charcoal In diethylene glycol dimethyl ether at 160℃; for 16h;	80%
With oxygen; sodium hydroxide at 200℃; for 10h; Neat (no solvent); neat (no solvent);	75%
With nitric oxide; sodium hydride In 1,4-dioxane at 20℃; for 24h;	43%
With oxygen; sodium hydroxide at 30 - 90℃; under 760.051 Torr; for 0.133333h; Kinetics; Catalytic behavior; Time; Microwave irradiation;

2-<(1-Ethylnonyl)sulfonyl>-1-phenyl-1-ethanon (85057-95-0) → sodium benzoate (532-32-1) + 1-Brommethylsulfonyl-1-ethylnonan (85058-00-0)

Conditions	Yield
With sodium hydroxide; bromine In ethanol for 12h; Ambient temperature;	A n/a B 91%

bromobenzene (108-86-1) + carbon monoxide (201230-82-2) → sodium benzoate (532-32-1) + sodium formate (141-53-7)

Conditions	Yield
With sodium hydroxide; tetraethylammonium iodide; triphenylphosphine; bis(benzonitrile)palladium(II) dichloride In water; m-xylene at 85 - 90℃; for 14h; Product distribution; influence of various PTC; effect of molar ratio;	A 90% B 9.3%

benzoic acid methyl ester (93-58-3) + sodium methylate (124-41-4) → methanol (67-56-1) + sodium benzoate (532-32-1) + Dimethyl ether (115-10-6) + benzoic acid benzyl ester (120-51-4)

Conditions	Yield
at 180℃;

benzoic acid methyl ester (93-58-3) + sodium methylate (124-41-4) → methanol (67-56-1) + sodium benzoate (532-32-1) + Dimethyl ether (115-10-6)

Conditions	Yield
at 175℃;

methanol (67-56-1) + phenylglyoxal hydrate (1074-12-0) + sodium methylate (124-41-4) → sodium benzoate (532-32-1)

methanol (67-56-1) + isoamyl benzoate (94-46-2) + sodium methylate (124-41-4) → sodium benzoate (532-32-1)

methanol (67-56-1) + benzoic acid benzyl ester (120-51-4) + sodium methylate (124-41-4) → sodium benzoate (532-32-1)

methanol (67-56-1) + acetic acid 1-bromo-2-oxo-2-phenyl-ethyl ester (53907-33-8) + sodium methylate (124-41-4) → benzoic acid methyl ester (93-58-3) + sodium benzoate (532-32-1)

benzoic acid phenyl ester (93-99-2) + 1,2-disodiotetraphenylethane (7381-16-0) → sodium benzoate (532-32-1) + biphenyl (92-52-4) + 1,1,2,2-tetraphenylethylene (632-51-9)

ethanol (64-17-5) + sodium benzoylacetonate → sodium benzoate (532-32-1) + benzoic acid ethyl ester (93-89-0) + ethyl acetate (141-78-6) + acetophenone (98-86-2)

Conditions	Yield
at 150℃;

benzoic acid ethyl ester (93-89-0) + sodium ethanolate (141-52-6) → sodium benzoate (532-32-1) + diethyl ether (60-29-7)

Conditions	Yield
at 160℃;

benzoyloxyacetonitrile (939-56-0) + sodium ethanolate (141-52-6) → sodium benzoate (532-32-1) + benzoic acid ethyl ester (93-89-0) + sodium cyanide (143-33-9)

phenyl sodium (1623-99-0) + methylammonium carbonate (15719-64-9, 15719-76-3, 97762-63-5) → sodium benzoate (532-32-1)

benzhydrol sodium salt (1204-50-8) → sodium benzoate (532-32-1) + Diphenylmethane (101-81-5) + benzene (71-43-2)

Conditions	Yield
at 250℃;

1,2-disodiotetraphenylethane (7381-16-0) + benzaldehyde (100-52-7) → sodium benzoate (532-32-1) + 1,1,2,2-tetraphenylethylene (632-51-9) + benzyl alcohol (100-51-6)

Conditions	Yield
folgendes Zersetzen mit Wasser; reagiert entsprechend mit Furfurol;

benzaldehyde (100-52-7) → sodium benzoate (532-32-1) + benzoic acid benzyl ester (120-51-4)

Conditions	Yield
With sodium amalgam beim Erhitzen im CO2-Strom;

nitromethane (75-52-5) + ethanol (64-17-5) + benzil (134-81-6) → sodium benzoate (532-32-1) + benzoic acid ethyl ester (93-89-0)

Conditions	Yield
Natriumverbindung reagiert;

sodium benzoate (532-32-1) + bis(2-chloromethyl)ether (542-88-1) → benzoyloxymethyl ether (131853-06-0)

Conditions	Yield
In N,N-dimethyl-formamide at 100℃;	100%
In N,N-dimethyl-formamide at 70℃; for 16h;	91%

sodium benzoate (532-32-1) + trans-2-(methoxycyclohexyl)methanesulphonate (7601-44-7, 90201-85-7, 93473-64-4) → cis-1-(benzoyloxy)-2-methoxycyclohexane (92864-37-4, 7429-22-3)

Conditions	Yield
In N,N-dimethyl-formamide for 6h; Heating;	100%

sodium benzoate (532-32-1) + 3-chloropentane-2,4-dione (1694-29-7) → benzoic acid 1-acetyl-2-oxopropyl ester (4620-47-7)

Conditions	Yield
In dimethyl sulfoxide for 3h;	100%
In dimethyl sulfoxide at 20℃; for 3h;

sodium benzoate (532-32-1) + 1-Bromo-2-butanone (816-40-0) → 3-oxo-2-butyl benzoate (80387-17-3)

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; for 3.75h;	100%

sodium benzoate (532-32-1) + 4-bromobutanenitrile (5332-06-9) → 4-benzoyloxybutyronitrile (75272-93-4)

Conditions	Yield
With tetra(n-butyl)ammonium hydrogensulfate In acetone for 4h; Molecular sieve; ethanol;	100%

sodium benzoate (532-32-1) + bis((4R,5S)-4-(bromomethyl)-5-phenyl-4,5-dihydrooxazol-2-yl)methane (1453106-62-1) → ((4S,4'S,5S,5'S)-2,2'-methylenebis(5-phenyl-4,5-dihydrooxazol-4,2-diyl))bis(methylene)dibenzoate (1453106-66-5)

Conditions	Yield
In dimethyl sulfoxide at 50℃; for 12h; Inert atmosphere; Schlenk technique; Sealed tube;	100%

sodium benzoate (532-32-1) + biphenyl-4-yl methanol (3597-91-9) → [1,1'-biphenyl]-4-ylmethyl benzoate (38418-12-1)

Conditions	Yield
Stage #1: biphenyl-4-yl methanol With 1,2-Diiodoethane; N,N-dimethyl-formamide; triphenylphosphine at 20℃; for 0.0166667h; Sealed tube; Inert atmosphere; Stage #2: sodium benzoate at 20℃; Sealed tube; Inert atmosphere;	100%

sodium benzoate (532-32-1) + C39H56N6O10SSi2 → 2-(((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)-2-(6-(N-(2-nitrobenzyl)benzamido)-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)ethyl benzoate

Conditions	Yield
In N,N-dimethyl-formamide at 20 - 90℃;	100%

sodium benzoate (532-32-1) + 2,3,2',3'-tetra-O-benzyl-4,6,4',6'-tetra-O-(methylsulfonyl)-α,α-trehalose (39021-76-6, 41548-14-5) → 4,6,4',6'-tetra-O-benzoyl-2,3,2',3'-tetra-O-benzyl-(α,-D-galactopyranosyl α-D-galactopyranoside) (41548-11-2)

Conditions	Yield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 130℃; for 20h;	99%

sodium benzoate (532-32-1) + 1,3-dichloro-2-(methoxymethoxy)propane (70905-45-2) → 2-(methoxymethoxy)-1,3-propanediyl dibenzoate (110874-21-0)

Conditions	Yield
With 15-crown-5 In N,N-dimethyl-formamide for 18h; Reflux;	99%
With 15-crown-5 In N,N-dimethyl-formamide for 48h; Heating;	95%

sodium benzoate (532-32-1) → benzoic acid-2,3,4,5,6-d5 (1079-02-3)

Conditions	Yield
With 10% Pt/activated carbon; water-d2 In isopropyl alcohol at 20℃; for 24h; Sealed tube; Inert atmosphere;	99%
With deuterated Raney nickel In water-d2 at 70 - 80℃; for 18h;

sodium benzoate (532-32-1) + 4-bromo-2,2,6,6-tetramethyl-3,5-heptanedione (39516-78-4) → 4-benzoyloxy-2,2,6,6-tetramethylheptan-3,5-dione (69825-65-6)

Conditions	Yield
In dimethyl sulfoxide for 3h;	99%

sodium benzoate (532-32-1) + 2-chloromethyl-3-chloroprop-1-ene (1871-57-4) → 1,3-dibenzoyl-(2-methylidene)-1,3-propanediol (39185-03-0)

Conditions	Yield
In N,N-dimethyl-formamide at 80℃; for 12h;	99%
In N,N-dimethyl-formamide for 4h; Heating;	73%

sodium benzoate (532-32-1) + (R)-1-O-benzyloxy-5-iodo-4-methylpentane (916235-41-1) → C20H24O3 (916235-46-6)

Conditions	Yield
In N,N-dimethyl-formamide	99%

sodium benzoate (532-32-1) + hexammine cobalt(III) chloride + water (7732-18-5) → sodium hexaamminecobalt(III) benzoate monohydrate

Conditions	Yield
In water dissolving of (Co(NH3)6)Cl3 (1 equiv.) in hot water, addn. of sodium benzoate (3 equiv.); slow cooling; crystn. for 6 days; filtration, crystn. from supernatant soln., combining of cryst.; drying in air; elem. anal.;	99%

sodium benzoate (532-32-1) + ((1R,3R,4R,7S)-7-(benzyloxy)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl methanesulfonate (1094603-22-1) → ((1R,3R,4R,7S)-7-(benzyloxy)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl benzoate (1094603-23-2)

Conditions	Yield
In dimethyl sulfoxide at 100℃; for 5h;	99%
In N,N-dimethyl-formamide at 90℃; for 18h;	97%
In N,N-dimethyl-formamide	97%

sodium benzoate (532-32-1) → sodium benzoate-d5 (62790-26-5)

Conditions	Yield
With 10% Pt/activated carbon; water-d2 In isopropyl alcohol at 20℃; for 24h; Sealed tube; Inert atmosphere;	99%

sodium benzoate (532-32-1) + (3,3-dimethylbutynyl)(phenyl)iodonium tosylate (92473-47-7) → iodobenzene (591-50-4) + 1-(3,3-dimethyl-1-butynyl) benzoate (104911-35-5)

Conditions	Yield
In dichloromethane on benzoate loaded Amberlyst column;	A 98% B 40%

sodium benzoate (532-32-1) + C44H74O21S2 (90653-39-7) → 1,3,4,6-tetra-O-pivaloyl-β-D-fructofuranosyl 4-O-benzoyl-2-O-mesyl-3,6-di-O-pivaloyl-α-D-galactopyranoside (90634-05-2)

Conditions	Yield
In N,N-dimethyl-formamide at 130℃; for 48h;	98%

sodium benzoate (532-32-1) + dimethylamino-3-O-methanesulfonyl-2-didesoxy-3,4-β-D,L-threo-pentopyranoside de methyle (87907-94-6, 87907-96-8) → O-benzoyl-3-dimethylamino-2-didesoxy-2,4-α-D,L-threo-pentopyranoside de methyle (87907-97-9, 87908-00-7)

Conditions	Yield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃; for 3h;	98%

sodium benzoate (532-32-1) + DL-(1,2/3,4,5)-1,2,3-tri-O-benzyl-4-O-methanesulfonyl-5-methanesulfonyloxymethyl-1,2,3,4-cyclohexanetetrol (125258-16-4) → DL-(1,2,4/3,5)-4-O-benzoyl-5-benzoyloxymethyl-1,2,3-tri-O-benzyl-1,2,3,4-cyclohexanetetrol (125258-19-7)

Conditions	Yield
In N,N-dimethyl-formamide at 120℃;	98%

sodium benzoate (532-32-1) + (2-(bromomethyl)benzyl)triphenyl-1-phosphonium bromide (67219-44-7) → [(o-benzoyloxymethyl)phenylmethyl]triphenylphosphonium bromide

Conditions	Yield
In water; acetone Ambient temperature;	98%

sodium benzoate (532-32-1) + methyl 2-phthalimido-2-deoxy-3,4,6-tris-(O-methanesulfonyl)-β-D-glucopyranoside (357399-55-4) → methyl 2-phthalimido-2-deoxy-4,6-bis-(O-benzoyl)-3-(O-methanesulfonyl)-β-D-galactopyranoside

Conditions	Yield
In N,N-dimethyl-formamide at 140℃; for 24h;	98%

sodium benzoate (532-32-1) + ((1R,3R,4R,7S)-3-(6-benzamido-9H-purin-9-yl)-7-(benzyloxy)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl methanesulfonate (293751-32-3) → ((1R,3R,4R,7S)-3-(6-benzamido-9H-purin-9-yl)-7-(benzyloxy)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methylbenzoate (293751-33-4)

Conditions	Yield
In dimethyl sulfoxide at 100℃; for 2h;	98%
In N,N-dimethyl-formamide at 90℃; for 7h;	88%
In N,N-dimethyl-formamide at 90℃; for 7h;	88%
In N,N-dimethyl-formamide	88%

methanol (67-56-1) + sodium benzoate (532-32-1) + lead(II) nitrate → [lead(II)(benzoate)2(methanol)2]

Conditions	Yield
In methanol Pb(NO3)2 (1 mmol) added to soln. of NaC6H5COO (2 mmol), stirred at 0°C for 30 min; toluene added, crystd. in refrigerator for 2 d; elem. anal.;	98%

trans-3-phenylprop-2-enyl chloride (21087-29-6) + sodium benzoate (532-32-1) → cinnamyl benzoate (5320-75-2)

Conditions	Yield
With (S)-[ruthenium(2-methyl-4-(C(CH3)3)-1-(COOCH2CH2P(phenyl)2))cyclopentadienyl)(CH3CN)2]PF6 In tetrahydrofuran at 25℃; for 7h; Inert atmosphere;	98%

trans-3-phenylprop-2-enyl chloride (21087-29-6) + sodium benzoate (532-32-1) → (R)-1-phenyl-2-propen-1-yl benzoate

Conditions	Yield
With (S)-[ruthenium(2-methyl-4-(C(CH3)3)-1-(COOCH2CH2P(phenyl)2))cyclopentadienyl)(CH3CN)2]PF6 In tetrahydrofuran at 25℃; for 2h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	98%

sodium benzoate (532-32-1) + (E)-1-(3-chloropropa-1-en-1-yl)-4-(trifluoromethyl)benzene (221527-77-1) → (R)-1-(4-trifluoromethylphenyl)-2-propenyl benzoate (1207287-91-9)

Conditions	Yield
With (S)-[ruthenium(2-methyl-4-(C(CH3)3)-1-(COOCH2CH2P(phenyl)2))cyclopentadienyl)(CH3CN)2]PF6 In tetrahydrofuran at 25℃; for 2h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	98%

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 
• 1074-12-0 phenylglyoxal hydrate 
• 120-51-4 benzoic acid benzyl ester 
• 93-99-2 benzoic acid phenyl ester 
• 7381-16-0 1,2-disodiotetraphenylethane 
• 64-17-5 ethanol 
• 939-56-0 benzoyloxyacetonitrile 
• 141-52-6 sodium ethanolate 
• 1623-99-0 phenyl sodium 
• 15719-64-9 methylammonium carbonate 
• 100-52-7 benzaldehyde 
• 75-52-5 nitromethane 

Downstream Products

• 94-33-7 C₉H₁₀O₃ 
• 5005-35-6 2-pyridyl benzoate 
• 85455-66-9 thiophen-2-yl-methyl benzoate 
• 1565-71-5 3-phenylpentan-3-ol 
• 77930-25-7 N-m-tolyl-dibenzamide 
• 61831-29-6 quinolin-2-ylmethyl benzoate 
• 7697-46-3 phenyl(1H-pyrrol-2-yl)methanone 
• 22915-73-7 hexane-1,6-diyl dibenzoate 
• 146855-63-2 1-benzoyloxy-6-bromohexane 
• 100622-11-5 5-benzoyloximethyl-furan-2-carboxylic acid methyl ester 
• 101094-15-9 5-benzoyloximethyl-furan-2-carboxylic acid ethyl ester 
• 14759-45-6 3-benzoyl-2-phenylindolizine 
• 102475-47-8 4-(4-phenylcarbonyloxybutoxy)butyl benzoate 
• 4620-46-6 benzoic acid 1-ethoxycarbonyl-2-oxopropyl ester 

Relevant academic research and scientific papers

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A simple, proficient, one-pot green chemical method for the biosynthesis of gold nanoparticles (AuNPs) with protein egg albumin by microwaves, which produce novel gold nanobiocatalyst (AuNBC) and it was characterized by FT-IR, UV-vis, TEM and DLS, which exhibited excellent stability over a wide range of pH and temperature. The catalytic activity of the as-synthesized AuNBC was quantified by synthesizing sodium benzoate from the one-pot oxidation of benzyl alcohol using gold nanobiocatalyst under microwave heating, which was stronger than AuNPs prepared by conventional chemical methods. The protocol is environmentally benign with non-toxic reagents, high recyclability and high efficiency.

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