Synthesis of 4,5-decamethyleneimidazole, 4,5-decamethyleneoxazole, 4,5-decamethyleneisoxazole, 4,5-decamethyleneimidazolone-2, and 4,5-decamethylenepyrazole from cyclodecanone derivatives

Article abstract of DOI:10.1007/BF00717350

4,5-Decamethyleneimidazole, 4,5-decamethyleneoxazole, and 4,5-decamethyleneimidazolone-2 were synthesized by reactions of 2-bromocyclododecanone and 2-hydroxycyclododecanone with formamide, ammonium formate, and urea, respectively.Condensation of 2-formylcyclododecanone with hydroxylamine and hydrazine hydrate resulted in 4,5-decamethyleneisoxazole, and 4,5-decamethylenepyrazole, respectively. - Key words: 2-bromocyclododecanone, 2-hydroxycyclododecanone; 4,5-decamethyleneimidazole, 4,5-decamethyleneoxazole, 4,5-decamethyleneimidazolone-2, 4,5-decamethyleneisoxazole, 4,5-decamethylenepyrazole.