170118-60-2Relevant articles and documents
β-Ethoxyvinyl polyfluoroalkyl ketones - versatile synthones in fluoroorganic chemistry
Gerus, I. I.,Gorbunova, M. G.,Kukhar, V. P.
, p. 195 - 198 (1994)
We have found readily available β-ethoxyvinyl trifluoromethyl ketone to be a convenient and comprehensive starting material for the synthesis of various fluoro-containing compounds such as heterocycles, enones, enaminones and chelate complexes.The 4,4,4-trifluoro-3-oxo-1-butenyl group formed by β-ethoxyvinyl trifluoromethyl ketone is a suitable protecting group for the N-H terminal of amino acids in peptide synthesis.The formation of peptides using these protected amino acids occurs without racemization. - Keywords: β-Ethoxyvinyl polyfluoroalkyl ketones; Synthones; Protecting group; Peptide synthesis; Reactions
3-Trifloxy-3-trifluoromethylpropeniminium triflate: Reaction with aromatic amines - An efficient synthesis of 2-trifluoromethylquinolines
Baraznenok, Ivan L.,Nenajdenko, Valentine G.,Balenkova, Elizabeth S.
, p. 937 - 941 (2007/10/03)
The reaction of iminium triflates 2 and 7 with various aromatic amines were investigated. The 2-R(f)-substituted quinolines 3 and 8 were prepared in excellent yields by the reaction of 2 and 7, respectively, with substituted anilines. The reactions of 2 a
