Journal of Inclusion Phenomena and Macrocyclic Chemistry
26. Oberlies, N.H., Kroll, D.J.: Camptothecin and taxol: historic
achievements in natural products research. J. Nat. Prod. 67(2),
129–135 (2004)
14. Stubbs, M., Mcsheehy, P.M.J., Grifths, J.R., Bashford, C.L.:
Causes and consequences of tumour acidity and implications for
treatment. Mol. Med. Today 6(1), 15–19 (2000)
27. Sirikantaramas, S., Yamazaki, M., Saito, K.: Mutations in topoi-
somerase i as a self-resistance mechanism coevolved with the pro-
duction of the anticancer alkaloid camptothecin in plants. Proc.
Natl. Acad. Sci. USA 105(18), 6782–6786 (2008)
15. Raghunand, N., He, X., Sluis, R.V., Mahoney, B., Baggett, B.,
Taylor, C.W., Painemurrieta, G., Roe, D., Bhujwalla, Z.M., Gil-
lies, R.J.: Enhancement of chemotherapy by manipulation of
tumour pH. Br. J. Cancer 80(7), 1005–1011 (1999)
28. Liu, L.F., Pu, D., Lin, C.T., Arpa, P.D., Wu, J.: Mechanism of
action of camptothecin. Ann. N. Y. Acad. Sci. 803(1), 44–49
(1996)
16. Wall, M., Wani, M., Cook, C., Palmer, K., Sim, G.: The isolation
and structure of camptothecin, a novel alkaloidal leukemia and
tumor inhibitor from Camptotheca acuminata. J. Am. Chem. Soc.
88(16), 3888–3890 (1996)
29. Soukasene, S., Toft, D.J., Moyer, T.J., Lu, H., Lee, H.K., Stand-
ley, S.M., Cryns, V.L., Stupp, S.I.: Antitumor activity of peptide
amphiphile nanofber-encapsulated camptothecin. ACS Nano
5(11), 9113 (2011)
17. Kawato, Y., Furuta, T., Aonuma, M., Yasuoka, M., Yokokura, T.,
Matsumoto, K.: Antitumor activity of a camptothecin derivative,
CPT-11, against human tumor xenografts in nude mice. Cancer
Chemother. Pharmacol. 28(3), 192–198 (1991)
30. Venditto, V.J., Simanek, E.E.: Cancer therapies utilizing the camp-
tothecins: a review of in vivo literature. Mol. Pharm. 7(2), 307
(2010)
18. Min, K.H., Park, K., Kim, Y.S., Bae, S.M., Lee, S., Jo, H.G.,
Park, R.W., Kim, I.S., Jeong, S.Y., Kim, K., Kwon, I.C.: Hydro-
phobically modifed glycol chitosan nanoparticles-encapsulated
camptothecin enhance the drug stability and tumor targeting in
cancer therapy. J. Control Release 127(3), 208–218 (2008)
19. Tang, X.J., Han, M., Yang, B., Shen, Y.Q., He, Z.G., Xu, D.H.,
Gao, J.Q.: Nanocarrier improves the bioavailability, stability and
antitumor activity of camptothecin. Int. J. Pharm. 477(1–2), 536–
545 (2014)
31. Liu, Y.Q., Li, W.Q., Morris-Natschke, S.L., Qian, K., Yang, L.,
Zhu, G.X., Wu, X.B., Chen, A.L., Zhang, S.Y., Nan, X., Lee,
K.H.: Perspectives on biologically active camptothecin deriva-
tives. Med. Res. Rev. 35(4), 753–789 (2015)
32. Wani, M.C.: Camptothecin and taxol—from nature to bench to
bedside. Hamdan Med. J. 8(1), 1–13 (2015)
33. Cheng, Y., Li, M., Xu, T.: Potential of poly(amidoamine) den-
drimers as drug carriers of camptothecin based on encapsulation
studies. Eur. J. Med. Chem. 43(8), 1791–1795 (2008)
34. Gavvala, K., Sengupta, A., Hazra, P.: Modulation of photophysics
and pKa shift of the anti-cancer drug camptothecin in the nano-
cavities of supramolecular hosts. ChemPhysChem 14(3), 532–542
(2013)
20. Kusari, S., Zühlke, S., Spiteller, M.: An endophytic fungus from
camptotheca acuminata that produces camptothecin and ana-
logues. J. Nat. Prod. 72(1), 2–7 (2009)
21. Dong, N., Xue, S.-F., Zhu, Q.-J., Tao, Z., Zhao, Y., Yang, L.-X.:
Cucurbit[n]urils (n=7, 8) binding of camptothecin and the efects
on solubility and reactivity of the anticancer drug. Supramol.
Chem. 20(7), 663–671 (2008)
35. Liao, R., Zhao, Y., Liao, X., Liu, M., Gao, C., Yang, J., Yang,
B.: Folic acid-polyamine-β-cyclodextrin for targeted delivery of
scutellarin to cancer cells. Polym. Adv. Technol. 26(5), 487–494
(2015)
22. Martins, S., Tho, I., Reimold, I., Fricker, G., Souto, E., Ferreira,
D., Brandl, M.: Brain delivery of camptothecin by means of solid
lipid nanoparticles: formulation design, in vitro and in vivo stud-
ies. Int. J. Pharm. 439(1–2), 49–62 (2012)
36. Zhang, B., Zavalij, P.Y., Isaacs, L.: Acyclic CB[n]-type molecular
containers: efect of solubilizing group on their function as solubi-
lizing excipients. Org. Biomol. Chem. 12(15), 2413–2422 (2014)
37. Lee, Y., Fukushima, S., Bae, Y., Hiki, S., Ishii, T., Kataoka, K.: A
protein nanocarrier from charge-conversion polymer in response
to endosomal pH. J. Am. Chem. Soc. 129(17), 5362–5363 (2007)
23. Liu, Y., Chen, X., Ding, J., Yu, L., Ma, D., Ding, J.: Improved
solubility and bioactivity of camptothecin family antitumor drugs
with supramolecular encapsulation by water-soluble pillar[6]
arene. ACS Omega 2(8), 5283–5288 (2017)
24. Li, X.Q., Wen, H.Y., Dong, H.Q., Xue, W.M., Pauletti, G.M., Cai,
X.J., Xia, W.J., Shi, D., Li, Y.Y.: Self-assembling nanomicelles of
a novel camptothecin prodrug engineered with a redox-responsive
release mechanism. Chem. Commun. 47(30), 8647–8649 (2011)
25. Watanabe, M., Kawano, K., Toma, K., Hattori, Y., Maitani,
Y.: In vivo antitumor activity of camptothecin incorporated in
liposomes formulated with an artifcial lipid and human serum
albumin. J. Control Release 127(3), 231–238 (2008)
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