1-Fluoro-2-nitrobenzene

Base Information Edit

Chemical Name:1-Fluoro-2-nitrobenzene
CAS No.:1493-27-2
Molecular Formula:C6H4FNO2
Molecular Weight:141.102
Hs Code.:29049085
European Community (EC) Number:216-088-0
NSC Number:51869
UNII:9WUK5DS6YX
DSSTox Substance ID:DTXSID1061730
Nikkaji Number:J47.807E
Wikidata:Q63398793
ChEMBL ID:CHEMBL49252
Mol file:1493-27-2.mol

Synonyms:1-fluoro-2-nitrobenzene;2-fluoronitrobenzene;o-fluoronitrobenzene;p-fluoronitrobenzene

Suppliers and Price of 1-Fluoro-2-nitrobenzene

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
o-Nitrofluorobenzene
50g
$ 180.00

TCI Chemical
2-Fluoronitrobenzene >98.0%(GC)
500g
$ 80.00

TCI Chemical
2-Fluoronitrobenzene >98.0%(GC)
100g
$ 63.00

TCI Chemical
2-Fluoronitrobenzene >98.0%(GC)
25g
$ 24.00

SynQuest Laboratories
2-Fluoronitrobenzene 99%
25 g
$ 15.00

SynQuest Laboratories
2-Fluoronitrobenzene 99%
100 g
$ 20.00

SynQuest Laboratories
2-Fluoronitrobenzene 99%
250 g
$ 39.00

Strem Chemicals
o-Fluoronitrobenzene
10g
$ 30.00

Strem Chemicals
o-Fluoronitrobenzene
50g
$ 84.00

Sigma-Aldrich
1-Fluoro-2-nitrobenzene 99%
250g
$ 201.00

Total 157 raw suppliers

Chemical Property of 1-Fluoro-2-nitrobenzene Edit

Chemical Property:

Appearance/Colour:clear yellow to brownish liquid
Vapor Pressure:0.000154mmHg at 25°C
Melting Point:-9 - -6 °C(lit.)
Refractive Index:n20/D 1.532(lit.)
Boiling Point:228.863 °C at 760 mmHg
Flash Point:94.444 °C
PSA：45.82000
Density:1.338 g/cm³
LogP:2.25710
Storage Temp.:Store below +30°C.
Solubility.:Chloroform, Ethyl Acetate, Methanol
Water Solubility.:immiscible
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:141.02260653
Heavy Atom Count:10
Complexity:134

Purity/Quality:

99% ^*data from raw suppliers

o-Nitrofluorobenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,T,Xi
Hazard Codes:Xi,T,Xn
Statements: 36/37/38-20/21/22
Safety Statements: 26-36-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Nitrogen Compounds -> Nitros, Aromatic
Canonical SMILES:C1=CC=C(C(=C1)[N+](=O)[O-])F
Uses o-Nitrofluorobenzene is an intermediate in the synthetic preparations of various pharmaceutical goods. 1-Fluoro-2-nitrobenzene is an intermediate in the synthetic preparations of various pharmaceutical goods.

Technology Process of 1-Fluoro-2-nitrobenzene

There total 70 articles about 1-Fluoro-2-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.1%

: 88-73-3
2-Chloronitrobenzene

: 1493-27-2,127723-77-7
ortho-nitrofluorobenzene

Guidance literature:: With potassium fluoride; polydiallyldimethylammonium chloride; In dimethyl sulfoxide; at 200 ℃; for 3h;
DOI:10.1016/j.jfluchem.2003.11.018

Reference yield: 76.8%

: 462-06-6
fluorobenzene

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 1493-27-2,127723-77-7
ortho-nitrofluorobenzene

Guidance literature:: With nitric acid; at 50 ℃; for 3h;
DOI:10.1039/c2ra21582a

Reference yield: 56.0%

: 609-73-4
o-nitroiodobenzene

: 98-95-3,26969-40-4
nitrobenzene

: 1493-27-2,127723-77-7
ortho-nitrofluorobenzene

Guidance literature:: o-nitroiodobenzene; With phenyllithium; In tetrahydrofuran; diethyl ether; cyclohexane; at -28 ℃; Flow reactor;

With 2-fluoro-3,3-dimethyl-2,3-dihydro-1,2-benzisothiazole-1,1-dioxide; In tetrahydrofuran; diethyl ether; cyclohexane; at -28 ℃; Flow reactor;
DOI:10.1002/asia.201201191