5-Hydroxytryptophan

Base Information Edit

Chemical Name:5-Hydroxytryptophan
CAS No.:56-69-9
Deprecated CAS:114-03-4,4298-20-8,72572-97-5,72572-98-6
Molecular Formula:C11H12N2O3
Molecular Weight:220.228
Hs Code.:2929909090
European Community (EC) Number:200-284-8,204-039-6
NSC Number:92523
UNII:9181P3OI6N
DSSTox Substance ID:DTXSID50859863
Nikkaji Number:J61.742C
Wikipedia:5-Hydroxytryptophan
Wikidata:Q27103541
NCI Thesaurus Code:C61712
Metabolomics Workbench ID:78505
ChEMBL ID:CHEMBL162789
Mol file:56-69-9.mol

Synonyms:5 Hydroxytryptophan;5-HTP;5-Hydroxy- Tryptophan;5-Hydroxytryptophan;Hydroxytryptophan;Oxitriptan;Oxytryptophan;Tryptophan, 5 Hydroxy;Tryptophan, 5-Hydroxy-

Suppliers and Price of 5-Hydroxytryptophan

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
DL-5-Hydroxytryptophan
50g
$ 342.00

Usbiological
DL-5-Hydroxytryptophan
1g
$ 199.00

TRC
5-HydroxyTryptophan
50mg
$ 65.00

TRC
5-HydroxyTryptophan
5g
$ 140.00

Sigma-Aldrich
5-Hydroxy-DL-tryptophan
5mg
$ 99.50

JR MediChem
Synephrine 98%
20mg
$ 300.00

DC Chemicals
5-Hydroxytryptophan >98%,StandardReferencesGrade
20 mg
$ 280.00

Crysdot
H-DL-Trp(5-OH)-OH 95+%
100g
$ 147.00

ChemScene
5-Hydroxytryptophan 99.91%
500g
$ 560.00

ChemScene
5-Hydroxytryptophan 99.91%
100g
$ 160.00

Total 249 raw suppliers

Chemical Property of 5-Hydroxytryptophan Edit

Chemical Property:

Appearance/Colour:White powder
Vapor Pressure:1.15E-11mmHg at 25°C
Melting Point:298-300 °C
Refractive Index:1.737
Boiling Point:520.6 °C at 760 mmHg
PKA:2.22±0.10(Predicted)
Flash Point:268.7 °C
PSA：99.34000
Density:1.484 g/cm³
LogP:1.52820
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
Water Solubility.:Soluble in water (4 mg/ml at 25°C), methanol.
XLogP3:-1.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:220.08479225
Heavy Atom Count:16
Complexity:272

Purity/Quality:

99%, ^*data from raw suppliers

DL-5-Hydroxytryptophan ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N
Recent ClinicalTrials:5HTP Regulation Of Asthma In Children
Description 5-Hydroxytryptophan (5-HTP) is an aromatic amino acid naturally produced by the body from the essential amino acid L-tryptophan (LT). Produced commercially by extraction from the seeds of the African plant, Griffonia simplicifolia, 5-HTP has been used clinically for over 30 years. The clinical efficacy of 5-HTP is due to its ability to increase production of serotonin in the brain.
Uses A metabolite of Tryptophan. 5-Hydroxytryptophan (5-HTP) is a direct 5-hydroxytryptamine (5-HT) precursor used to assess central serotonergic function. 5-Hydroxytryptophan (5-HTP) is an intermediate in the natural synthesis of the essential amino acid, tryptophan, to serotonin. Clinical studies suggest that 5-HTP supports healthy serotonin levels. In the body, 5-HTP converts to serotonin with the enzymatic removal of a carboxyl group (COOH). Serotonin is an important neurotransmitter involved in the regulation of endocrine and brain activity responsible for emotion, appetite and sleep/wake cycles.
Therapeutic Function Antidepressant, Antiepileptic

Technology Process of 5-Hydroxytryptophan

There total 29 articles about 5-Hydroxytryptophan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: