Ethyl 4-anilino-2-methylpyrimidine-5-carboxylate

Base Information

Chemical Name:Ethyl 4-anilino-2-methylpyrimidine-5-carboxylate
CAS No.:69731-60-8
Molecular Formula:C14H15N3O2
Molecular Weight:257.2878
Hs Code.:
NSC Number:165334
DSSTox Substance ID:DTXSID20304299
Wikidata:Q82050136

Synonyms:69731-60-8;ethyl 4-anilino-2-methylpyrimidine-5-carboxylate;NSC165334;DTXSID20304299;NSC-165334

Suppliers and Price of Ethyl 4-anilino-2-methylpyrimidine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethyl 4-anilino-2-methylpyrimidine-5-carboxylate

Chemical Property:

Vapor Pressure:1.72E-06mmHg at 25°C
Boiling Point:396.3°C at 760 mmHg
Flash Point:193.5°C
Density:1.21g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:257.116426730
Heavy Atom Count:19
Complexity:292

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN=C(N=C1NC2=CC=CC=C2)C

Technology Process of Ethyl 4-anilino-2-methylpyrimidine-5-carboxylate

There total 2 articles about Ethyl 4-anilino-2-methylpyrimidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 13061-96-6
dihydroxy-methyl-borane

: 280581-48-8
4-phenylamino-2-chloropyrimidine-5-carboxylic acid ethyl ester

: 69731-60-8
ethyl 2-methyl-4-(phenylamino)pyrimidine-5-carboxylate

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In toluene; at 100 ℃; for 8h; Inert atmosphere; Sealed tube;
DOI:10.1002/adsc.202100444