4-chlorobenzenesulfinyl Chloride

Base Information

• Chemical Name: 4-chlorobenzenesulfinyl Chloride
• CAS No.: 2901-92-0
• Molecular Formula: C6H4Cl2OS
• Molecular Weight: 195.069
• DSSTox Substance ID: DTXSID50455384
• Nikkaji Number: J497.712B
• Mol file: 2901-92-0.mol

Synonyms:4-chlorobenzenesulfinyl Chloride;2901-92-0;4-chlorobenzene-1-sulfinyl chloride;4-Chlorobenzenesulfinic chloride;p-chlorophenylsulfinyl chloride;Benzenesulfinyl chloride, 4-chloro-;starbld0045027;SCHEMBL5520567;DTXSID50455384;MFCD21882005;AKOS016370532;NS-01908;F71119

Chemical Property of 4-chlorobenzenesulfinyl Chloride

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 193.9359913
• Heavy Atom Count: 10
• Complexity: 132

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1S(=O)Cl)Cl

Technology Process of 4-chlorobenzenesulfinyl Chloride

There total 9 articles about 4-chlorobenzenesulfinyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(2-((4- chlorophenyl)sulfinyl)ethyl)trimethylsilane (143505-43-5) → p-chlorophenylsulfinyl chloride (2901-92-0) + 2-(trimethylsilyl)ethyl chloride (17336-78-6)

Guidance literature:

With sulfuryl dichloride; In dichloromethane; for 3h; -78 deg C -> r.t.;

DOI:10.1016/0040-4039(92)88076-H

Reference yield: 89.0%

4-chlorobenzenesulfinic acid (100-03-8) → p-chlorophenylsulfinyl chloride (2901-92-0)

Guidance literature:

With thionyl chloride; In pentane;

DOI:10.1055/s-1991-26365

Reference yield: 72.0%

chlorobenzene (108-90-7) → p-chlorophenylsulfinyl chloride (2901-92-0)

Guidance literature:

With thionyl chloride; Montmorillonite K-10 clay; In chloroform; at 50 ℃; for 6h;

DOI:10.1055/s-2001-17437

upstream raw materials:

4-chlorobenzenesulfinic acid

(2-((4- chlorophenyl)sulfinyl)ethyl)trimethylsilane

N-(4-chloro-phenylsulfanylmethyl)-phthalimide

chlorobenzene

Downstream raw materials:

benzyl 4-chlorobenzenesulfinate

4-Chloro-benzenesulfinyl isocyanate

N-Triphenylphosphoranyliden-4-chlor-benzolsulfinsaeureamid

[(4-Chloro-benzenesulfinyl)-phenyl-methylene]-triphenyl-λ⁵-phosphane

Refernces

• 1、 Guo, Junkai,Kuang, Cuiwen,Rong, Jian,Li, Lingchun,Ni, Chuanfa,Hu, Jinbo. "Rapid Deoxyfluorination of Alcohols with N-Tosyl-4-chlorobenzenesulfonimidoyl Fluoride (SulfoxFluor) at Room Temperature". supporting information. p. 7259 - 7264. Retrieved 2019/05/10.
• 2、 Liang, Chungen,Collet, Florence,Robert-Peillard, Fabien,Mueller, Paul,Dodd, Robert H.,Dauban, Philippe. "Toward a synthetically useful stereoselective C-H amination of hydrocarbons". . p. 343 - 350. Retrieved 2008/10/09.