3-Chloro-5-methylaniline

Base Information

Chemical Name:3-Chloro-5-methylaniline
CAS No.:29027-20-1
Molecular Formula:C7H8ClN
Molecular Weight:141.6
Hs Code.:2921430090
European Community (EC) Number:813-805-4
DSSTox Substance ID:DTXSID10499683
Nikkaji Number:J153.389D
Wikidata:Q72453596
Mol file:29027-20-1.mol

Synonyms:3-chloro-5-methylaniline;29027-20-1;Benzenamine, 3-chloro-5-methyl-;3-CHLORO-5-METHYLBENZENAMINE;MFCD15527197;3-Chloro-5-methylbenzenamine;3-Chloro-5-methylaniline;3-Chloro-5-methylphenylamine;3-chloro-5-methyl-aniline;3- Chloro-5-methylbenzenamine;3-chloro-5-methyl-phenylamine;SCHEMBL2098422;DTXSID10499683;XUZCJDBXXYJXDD-UHFFFAOYSA-N;AMY40995;CL8423;AKOS006339900;CS-W019843;AC-28548;DS-14504;SY020704;FT-0686987;EN300-207961;A876551;J-512280

Suppliers and Price of 3-Chloro-5-methylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Chloro-5-methylaniline
1g
$ 75.00

TRC
3-Chloro-5-methylaniline
100mg
$ 45.00

SynQuest Laboratories
3-Chloro-5-methylaniline
100 g
$ 772.00

SynQuest Laboratories
3-Chloro-5-methylaniline
25 g
$ 221.00

SynQuest Laboratories
3-Chloro-5-methylaniline
5 g
$ 56.00

Oakwood
3-Chloro-5-methylaniline 99%
1g
$ 18.00

Oakwood
3-Chloro-5-methylaniline 99%
5g
$ 58.00

Medical Isotopes, Inc.
3-Chloro-5-methylaniline 95+%
5 g
$ 379.00

Matrix Scientific
3-Chloro-5-methylaniline 95+%
5g
$ 468.00

Matrix Scientific
3-Chloro-5-methylaniline 95+%
1g
$ 121.00

Total 42 raw suppliers

Chemical Property of 3-Chloro-5-methylaniline

Chemical Property:

Boiling Point:248.6±20.0℃ (760 Torr)
PKA:3.66±0.10(Predicted)
Flash Point:104.1±21.8℃
PSA：26.02000
Density:1.180±0.06 g/cm3 (20 oC 760 Torr)
LogP:2.81180
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Sensitive.:Light Sensitive
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:141.0345270
Heavy Atom Count:9
Complexity:94.9

Purity/Quality:

97% ^*data from raw suppliers

3-Chloro-5-methylaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)Cl)N

Technology Process of 3-Chloro-5-methylaniline

There total 9 articles about 3-Chloro-5-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 16582-38-0
3-chloro-5-nitrotoluene

: 29027-20-1
3-chloro-5-methylaniline

Guidance literature:: With tin(II) chloride dihdyrate; In ethanol; for 3h; Reflux;

Reference yield:

: 5465-33-8
2-chloro-4-methyl-6-nitroaniline

: 29027-20-1
3-chloro-5-methylaniline

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid; aq. sodium nitrite / ethanol / 0.5 h / 0 - 20 °C

1.2: 69 percent / ethanol; H₂O / Heating

2.1: 93 percent / tin(II) chloride dihydrate / ethanol / 3 h / Heating

With sulfuric acid; tin(ll) chloride; sodium nitrite; In ethanol;
DOI:10.1021/jm000199q

Reference yield:

: 89-62-3
4-methyl-2-nitroaniline

: 29027-20-1
3-chloro-5-methylaniline

Guidance literature:: Multi-step reaction with 3 steps

1.1: 29 percent / N-chlorosuccinimide / acetonitrile / Heating

2.1: sulfuric acid; aq. sodium nitrite / ethanol / 0.5 h / 0 - 20 °C

2.2: 69 percent / ethanol; H₂O / Heating

3.1: 93 percent / tin(II) chloride dihydrate / ethanol / 3 h / Heating

With N-chloro-succinimide; sulfuric acid; tin(ll) chloride; sodium nitrite; In ethanol; acetonitrile;
DOI:10.1021/jm000199q