2-Phenoxy-1-(4-phenylphenyl)ethanone

Base Information

Chemical Name:2-Phenoxy-1-(4-phenylphenyl)ethanone
CAS No.:29263-70-5
Molecular Formula:C20H16O2
Molecular Weight:288.346
Hs Code.:
European Community (EC) Number:661-205-4
Nikkaji Number:J1.369.099E
Mol file:29263-70-5.mol

Synonyms:1-biphenyl-4-yl-2-phenoxy-ethanone;29263-70-5;1-{[1,1'-biphenyl]-4-yl}-2-phenoxyethan-1-one;2-phenoxy-1-(4-phenylphenyl)ethanone;SCHEMBL9787024;MFCD00156690;AKOS022160952;2-PHENOXY-4'-PHENYLACETOPHENONE;1-Biphenyl-4-yl-2-phenoxy-ethanone, 97%

Suppliers and Price of 2-Phenoxy-1-(4-phenylphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Phenoxy-1-(4-phenylphenyl)ethanone

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:288.115029749
Heavy Atom Count:22
Complexity:332

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)COC3=CC=CC=C3

Technology Process of 2-Phenoxy-1-(4-phenylphenyl)ethanone

There total 5 articles about 2-Phenoxy-1-(4-phenylphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 135-73-9
2-Bromo-4'-phenylacetophenone

: 108-95-2,27073-41-2
phenol

: 29263-70-5
1-([1,1'-biphenyl]-4-yl)-2-phenoxyethan-1-one

Guidance literature:: With potassium carbonate; In acetone; Reflux;
DOI:10.1021/acs.orglett.0c02117

Reference yield: 52.0%

: 36372-16-4
1-(4-bromophenyl)-2-phenoxyethan-1-one

: 98-80-6
phenylboronic acid

: 29263-70-5
1-([1,1'-biphenyl]-4-yl)-2-phenoxyethan-1-one

Guidance literature:: With potassium phosphate; palladium diacetate; triphenylphosphine; In 1,4-dioxane; methanol; at 90 ℃; for 20h; Schlenk technique; Inert atmosphere;
DOI:10.1002/cmdc.201300354

Reference yield:

: 99-73-0,132309-76-3
para-bromophenacyl bromide

: 29263-70-5
1-([1,1'-biphenyl]-4-yl)-2-phenoxyethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / butanone / 0.5 h

1.2: 10 h / Reflux

2.1: potassium phosphate; triphenylphosphine; palladium diacetate / 1,4-dioxane; methanol / 20 h / 90 °C / Schlenk technique; Inert atmosphere

With potassium phosphate; palladium diacetate; potassium carbonate; triphenylphosphine; In 1,4-dioxane; methanol; butanone; 2.1: |Suzuki Coupling;
DOI:10.1002/cmdc.201300354