(2S)-2-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID

Base Information

• Chemical Name: (2S)-2-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID
• CAS No.: 29268-18-6
• Molecular Formula: C9H11NO4S
• Molecular Weight: 229.257
• Mol file: 29268-18-6.mol

Synonyms:(S)-2-phenylsulfonylamino-propionic acid;N-benzenesulfonylalanine;(S)-2-(phenylsulfonamido)propanoic acid;N-(phenylsulfonyl)-L-alanine;N-phenylsulfonyl-(S)-alanine;(2S)-2-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID;

Chemical Property of (2S)-2-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID

Chemical Property:

• Melting Point: 123-125 °C
• Boiling Point: 423.1±47.0 °C(Predicted)
• PKA: 3.50±0.10(Predicted)
• PSA: 91.85000
• Density: 1.364±0.06 g/cm3(Predicted)
• LogP: 1.90970

Purity/Quality:

99% ^*data from raw suppliers

N-(Phenylsulfonyl)-L-alanine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2S)-2-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID

There total 5 articles about (2S)-2-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

L-alanin (56-41-7,25191-17-7,18875-37-1) + benzenesulfonyl chloride (98-09-9) → (2S)-2-[(phenylsulfonyl)amino]propanoic acid (29268-18-6,42908-31-6)

Guidance literature:

In sodium hydroxide; water; at 60 ℃;

DOI:10.1021/ja00410a030

Reference yield: 62.0%

benzenesulfonyl chloride (98-09-9) + L-Ala (25191-17-7,18875-37-1) → (2S)-2-[(phenylsulfonyl)amino]propanoic acid (29268-18-6,42908-31-6)

Guidance literature:

Reference yield:

→ (2S)-2-[(phenylsulfonyl)amino]propanoic acid (29268-18-6,42908-31-6)

Guidance literature:

With Norpseudoephedrine; water; das Salz des Benzolsulfonyl-d(-)-alanins faellt zuerst aus;

upstream raw materials:

L-alanin

benzenesulfonyl chloride

L-Ala

Downstream raw materials:

N-(phenylsulfonyl)-L-alanyl chloride

N-phenylsulfonyl-L-alanine methyl ester

N-(1-hydrazinocarbonyl-ethyl)-benzenesulfonamide