(6-Bromohex-1-EN-1-YL)benzene

Base Information

• Chemical Name: (6-Bromohex-1-EN-1-YL)benzene
• CAS No.: 295324-71-9
• Molecular Formula: C12H15Br
• Molecular Weight: 239.155
• DSSTox Substance ID: DTXSID20707529
• Mol file: 295324-71-9.mol

Synonyms:(6-BROMOHEX-1-EN-1-YL)BENZENE;295324-71-9;6-bromo-1-phenyl-1-hexene;DTXSID20707529

Chemical Property of (6-Bromohex-1-EN-1-YL)benzene

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 5
• Exact Mass: 238.03571
• Heavy Atom Count: 13
• Complexity: 134

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CCCCCBr

Technology Process of (6-Bromohex-1-EN-1-YL)benzene

There total 5 articles about (6-Bromohex-1-EN-1-YL)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-phenylhex-5-en-1-ol (98078-15-0) → (E/Z)-(6-bromohex-1-enyl)-benzene (295324-71-9)

Guidance literature:

With pyridine; phosphorus tribromide; In diethyl ether; at 0 - 25 ℃; for 8h;

DOI:10.1080/10426500008082398

Reference yield:

1,5-dibromo-pentane (111-24-0) + benzaldehyde (100-52-7) → (E/Z)-(6-bromohex-1-enyl)-benzene (295324-71-9)

Guidance literature:

1,5-dibromo-pentane; With triphenylphosphine; In 5,5-dimethyl-1,3-cyclohexadiene; for 12h; Reflux;

benzaldehyde; With potassium carbonate; In tetrahydrofuran; for 12h; Reflux;

DOI:10.1039/c1ob05082f

Reference yield:

1,5-dibromo-pentane (111-24-0) → (E/Z)-(6-bromohex-1-enyl)-benzene (295324-71-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 5,5-dimethyl-1,3-cyclohexadiene / 12 h / Reflux

2: potassium carbonate / tetrahydrofuran / 12 h / Reflux

With potassium carbonate; In tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; 2: Wittig reaction;

DOI:10.1002/ejoc.201100876

upstream raw materials:

6-phenylhex-5-en-1-ol

benzaldehyde

5-hydroxypentyltriphenylphosphonium bromide

1,5-dibromo-pentane

Downstream raw materials:

C₂₁H₂₀ClNO

C₂₁H₂₀ClNO

2-cyclopentyl-2-phenylacetic acid

C₂₄H₃₀