Ethyl (1-methyl-1H-indol-3-yl)(oxo)acetate

Base Information

Chemical Name:Ethyl (1-methyl-1H-indol-3-yl)(oxo)acetate
CAS No.:25055-54-3
Molecular Formula:C13H13 N O3
Molecular Weight:231.25
Hs Code.:2918300090
NSC Number:106238
DSSTox Substance ID:DTXSID90295908
Wikidata:Q82036129
Mol file:25055-54-3.mol

Synonyms:25055-54-3;ethyl 2-(1-methylindol-3-yl)-2-oxoacetate;Ethyl (1-methyl-1H-indol-3-yl)(oxo)acetate;NSC106238;SCHEMBL4685270;DTXSID90295908;NSC-106238;ethyl 2-(1-methyl 1h-indol-3-yl)-2-oxoacetate;ethyl-2-(1-methyl-1H-indol-3-yl)-2-oxoacetate;ETHYL 2-(1-METHYLINDOL-3-YL)-2-OXO-ACETATE

Suppliers and Price of Ethyl (1-methyl-1H-indol-3-yl)(oxo)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL-2-(1-METHYL-1H-INDOL-3-YL)-2-OXOACETATE 95.00%
5MG
$ 497.55

Total 5 raw suppliers

Chemical Property of Ethyl (1-methyl-1H-indol-3-yl)(oxo)acetate

Chemical Property:

Vapor Pressure:5.18E-06mmHg at 25°C
Boiling Point:381.2°Cat760mmHg
Flash Point:184.3°C
PSA：48.30000
Density:1.18g/cm³
LogP:1.92410
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:231.08954328
Heavy Atom Count:17
Complexity:316

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-2-(1-METHYL-1H-INDOL-3-YL)-2-OXOACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=O)C1=CN(C2=CC=CC=C21)C

Technology Process of Ethyl (1-methyl-1H-indol-3-yl)(oxo)acetate

There total 11 articles about Ethyl (1-methyl-1H-indol-3-yl)(oxo)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: C₁₃H₁₄N₂O₂

: 25055-54-3
ethyl 2-(1-methyl-1H-indol-3-yl)-2-oxoacetate

Guidance literature:: With hydrogenchloride; water; at 20 ℃; for 0.5h;
DOI:10.1021/acs.joc.6b02176

Reference yield:

: 603-76-9
1-methylindole

: 25055-54-3
ethyl 2-(1-methyl-1H-indol-3-yl)-2-oxoacetate

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether; tetrahydrofuran / 0 - 20 °C

2: diethyl ether; tetrahydrofuran; ethanol / -60 - 20 °C

In tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1021/ja068969w

Reference yield:

: C₂₀H₁₉F₃N₂O₂

: 25055-54-3
ethyl 2-(1-methyl-1H-indol-3-yl)-2-oxoacetate

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; water; lithium perchlorate; In acetonitrile; at 20 ℃; for 12h; Electrolysis;
DOI:10.1021/acs.orglett.9b02433