Ethyl chloroglyoxylate

Base Information Edit

Chemical Name:Ethyl chloroglyoxylate
CAS No.:4755-77-5
Molecular Formula:C4H5ClO3
Molecular Weight:136.535
Hs Code.:29171990
European Community (EC) Number:225-285-0
NSC Number:80644
DSSTox Substance ID:DTXSID3063598
Nikkaji Number:J1.829E
Wikidata:Q72476428
Mol file:4755-77-5.mol

Synonyms:ethoxalyl chloride

Suppliers and Price of Ethyl chloroglyoxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
EthoxyoxalylChloride
100g
$ 85.00

TRC
EthoxyoxalylChloride
25g
$ 45.00

TCI Chemical
Ethyl Chloroglyoxylate >98.0%(T)
500g
$ 202.00

TCI Chemical
Ethyl Chloroglyoxylate >98.0%(T)
25g
$ 26.00

TCI Chemical
Ethyl Chloroglyoxylate >98.0%(T)
100g
$ 70.00

SynQuest Laboratories
Ethyl 2-chloro-2-oxoacetate 97%
100 g
$ 75.00

SynQuest Laboratories
Ethyl 2-chloro-2-oxoacetate 97%
250 g
$ 150.00

Sigma-Aldrich
Ethyl chlorooxoacetate 98%
500g
$ 227.00

Sigma-Aldrich
Ethyl chlorooxoacetate 98%
100g
$ 82.20

Sigma-Aldrich
Ethyl chlorooxoacetate 98%
25g
$ 37.50

Total 112 raw suppliers

Chemical Property of Ethyl chloroglyoxylate Edit

Chemical Property:

Appearance/Colour:clear liquid
Vapor Pressure:7.19mmHg at 25°C
Melting Point:135oC
Refractive Index:1.416-1.418
Boiling Point:137 °C at 760 mmHg
Flash Point:41.7 °C
PSA：43.37000
Density:1.281 g/cm³
LogP:0.31490
Storage Temp.:Flammables area
Sensitive.:Moisture Sensitive
Water Solubility.:Slightly miscible with water.
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:135.9927217
Heavy Atom Count:8
Complexity:110

Purity/Quality:

99% ^*data from raw suppliers

EthoxyoxalylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): C, F
Hazard Codes:C,F
Statements: 34-29-20/21/22-14-10-37-36
Safety Statements: 8-45-36/37/39-26-16

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Toxic Gases & Vapors -> Acid Halides
Canonical SMILES:CCOC(=O)C(=O)Cl
Uses Ethyl oxalyl monochloride is used in the synthesis of 2-oxo-3-alkenoic esters and alpha-keto ester in good yield. Ethyl oxalyl monochloride acts as a reactant in the preparation of oxyoxalamide derivatives as an epoxide hydrolase inhibitor. Ethyl oxalyl chloride is used in the synthesis of 2-oxo-3-alkenoic esters and alpha-keto ester in good yield. It acts as a reactant in the preparation of oxyoxalamide derivatives as an epoxide hydrolase inhibitor. Ethyl chlorooxoacetate can be used for the synthesis of:α-keto esters.Functionalized 3-pyrolin-2-ones.Substituted arylglyoxylic acids via Friedel–Crafts acylation.Substituted 9,10-phenanthrenequinones.Quinoxalinone derivatives.

Technology Process of Ethyl chloroglyoxylate

There total 18 articles about Ethyl chloroglyoxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.7%

: 95-92-1
oxalic acid diethyl ester

: 75-00-3
chloroethane

: 4755-77-5
Ethyl oxalyl chloride

Guidance literature:: With phosphorus pentachloride; at 90 ℃; for 5h;

Reference yield: 83.7%

: 95-92-1
oxalic acid diethyl ester

: 79-37-8
oxalyl dichloride

: 75-00-3
chloroethane

: 63938-37-4
1,2-diethoxy-tetrachloro-ethane

: 98019-44-4
ethoxy-dichloro-acetyl chloride

: 4755-77-5
Ethyl oxalyl chloride

Guidance literature:: With phosphorus pentachloride; manganese(ll) chloride; at 90 ℃; for 5h; Product distribution; other catalysts (CuCl₂, ZnCl₂, CdCl₂, CrCl₃, FeCl₃, CoCl₂, PdCl₂) and temperatures (from 70 to 130 deg C);