(16E)-16-Benzylidene-3beta-hydroxy-5alpha-androsta-17-one

Base Information

• Chemical Name: (16E)-16-Benzylidene-3beta-hydroxy-5alpha-androsta-17-one
• CAS No.: 60536-96-1
• Molecular Formula: C26H34O2
• Molecular Weight: 378.555
• NSC Number: 67585
• DSSTox Substance ID: DTXSID30418179
• Nikkaji Number: J3.584.063J
• Wikidata: Q82228548

Synonyms:60536-96-1;AC1NS9UR;DTXSID30418179;NSC67585;NSC-67585;J3.584.063J;(16E)-16-Benzylidene-3beta-hydroxy-5alpha-androsta-17-one

Chemical Property of (16E)-16-Benzylidene-3beta-hydroxy-5alpha-androsta-17-one

Chemical Property:

• Vapor Pressure: 4.48E-12mmHg at 25°C
• Boiling Point: 530.3°C at 760 mmHg
• Flash Point: 223.8°C
• Density: 1.128g/cm³
• XLogP3: 5.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 378.255880323
• Heavy Atom Count: 28
• Complexity: 659

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC(CC1CCC3C2CCC4(C3CC(=CC5=CC=CC=C5)C4=O)C)O
• Isomeric SMILES: C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3C/C(=C\C5=CC=CC=C5)/C4=O)C)O

Technology Process of (16E)-16-Benzylidene-3beta-hydroxy-5alpha-androsta-17-one

There total 2 articles about (16E)-16-Benzylidene-3beta-hydroxy-5alpha-androsta-17-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Epiandrosterone (481-29-8) + benzaldehyde (100-52-7) → (3S,5S,8R,9S,10S,13S,14S)-3-Hydroxy-10,13-dimethyl-16-[1-phenyl-meth-(Z)-ylidene]-hexadecahydro-cyclopenta[a]phenanthren-17-one (60536-96-1)

Guidance literature:

With potassium hydroxide;

DOI:10.1039/j39700000244

Reference yield:

→ (3S,5S,10S,13R)-3-Hydroxy-10,13-dimethyl-16-[1-phenyl-meth-(Z)-ylidene]-hexadecahydro-cyclopenta[a]phenanthren-17-one (38456-50-7,60536-96-1)

Guidance literature:

10, Na-methoxid in Me., Benzaldehyd;

DOI:10.1021/jo00947a004

Reference yield: 93.0%

(3S,5S,8R,9S,10S,13S,14S)-3-Hydroxy-10,13-dimethyl-16-[1-phenyl-meth-(Z)-ylidene]-hexadecahydro-cyclopenta[a]phenanthren-17-one (60536-96-1) + acetylacetone (123-54-6,81235-32-7) → 1'-oxo-5'-phenyl-6'-acetylandrostano[17,16-c]yclohex-2'-en-3-ol

Guidance literature:

With sodium ethanolate; for 7h; Reflux;

DOI:10.1134/S106816201405001X

upstream raw materials:

Epiandrosterone

benzaldehyde

Downstream raw materials:

16-Benzyliden-5α-androstan-3β-ol

16-Benzyliden-5α-androstan-3-on

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 60536-96-1 (3beta,5alpha,16E)-3-hydroxy-16-(phenylmethylidene)androstan-17-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send