Piperidine, 1-(phenylmethyl)-, 1-oxide

Base Information

Chemical Name:Piperidine, 1-(phenylmethyl)-, 1-oxide
CAS No.:29872-25-1
Molecular Formula:C12H17NO
Molecular Weight:191.273
Hs Code.:
DSSTox Substance ID:DTXSID50476913
Nikkaji Number:J1.027.864C
Wikidata:Q82308844
Mol file:29872-25-1.mol

Synonyms:29872-25-1;Piperidine, 1-(phenylmethyl)-, 1-oxide;SCHEMBL596253;DTXSID50476913;InChI=1/C12H17NO/c14-13(9-5-2-6-10-13)11-12-7-3-1-4-8-12/h1,3-4,7-8H,2,5-6,9-11H

Suppliers and Price of Piperidine, 1-(phenylmethyl)-, 1-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Piperidine, 1-(phenylmethyl)-, 1-oxide

Chemical Property:

PSA：29.43000
LogP:2.64390
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:191.131014166
Heavy Atom Count:14
Complexity:169

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC[N+](CC1)(CC2=CC=CC=C2)[O-]

Technology Process of Piperidine, 1-(phenylmethyl)-, 1-oxide

There total 7 articles about Piperidine, 1-(phenylmethyl)-, 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 2905-56-8
N-Benzylpiperidine

: 29872-25-1
N-benzylpiperidine N-oxide

Guidance literature:: With dihydrogen peroxide; benzonitrile; Mg-Al-O-t-Bu HT (Catalyst B); In methanol; water; at 65 ℃; for 0.75h; Product distribution / selectivity;

Reference yield:

: 17206-00-7
N-methylpiperidine-N-oxide

: 29872-25-1
N-benzylpiperidine N-oxide

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 0.5 h / 0 °C

2: 1.) MeLi; 2.) tetrabutylammonium fluoride / 1.) THF, RT, 1 h; 2.) THF, 110 deg C, 10 h, sealed tube

3: 30 percent hydrogen peroxide

With tetrabutyl ammonium fluoride; methyllithium; dihydrogen peroxide; In dichloromethane;
DOI:10.1246/bcsj.60.3291

Reference yield:

: 110-89-4
piperidine

: 29872-25-1
N-benzylpiperidine N-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / K₂CO₃ / tetrahydrofuran / 20 h / 40 °C

2: dimethyldioxirane / acetone; CH₂Cl₂ / 0 °C

With 3,3-dimethyldioxirane; potassium carbonate; In tetrahydrofuran; dichloromethane; acetone;
DOI:10.1016/S0040-4020(97)10048-5