2,6-Piperidinedione, 3-amino-, (3S)-

Base Information

Chemical Name:2,6-Piperidinedione, 3-amino-, (3S)-
CAS No.:29883-25-8
Molecular Formula:C5H8N2O2
Molecular Weight:128.131
Hs Code.:
DSSTox Substance ID:DTXSID90475187
Nikkaji Number:J3.510.168C
Wikidata:Q82305491
Mol file:29883-25-8.mol

Synonyms:29883-25-8;2,6-Piperidinedione, 3-amino-, (3S)-;(3S)-3-aminopiperidine-2,6-dione;(S)-3-Amino-piperidine-2,6-dione;(S)-3-Aminopiperidine-2,6-dione;pyroglutamine;3-amino-1,6-dioxopiperidine;a-Aminoglutarimide;L-2-Aminoglutarimide;l-glutamic acid imide;Aminoglutarimide, L-2-;SCHEMBL444005;3beta-Aminopiperidine-2,6-dione;DTXSID90475187;AC9237;AKOS006337482;J3.510.168C;EN300-131842;(3S)-3-azanylpiperidine-2,6-dione;(S)-2-Aminoglutarimide

Suppliers and Price of 2,6-Piperidinedione, 3-amino-, (3S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
(S)-3-Amino-piperidine-2,6-dione 96%
1g
$ 298.00

J&W Pharmlab
(S)-3-Amino-piperidine-2,6-dione 96%
500mg
$ 198.00

AK Scientific
2,6-Piperidinedione,3-amino-,(3S)-
5g
$ 998.00

AccelPharmtech
(3S)-3-amino-2,6-Piperidinedione 97.00%
25G
$ 3990.00

AccelPharmtech
(3S)-3-amino-2,6-Piperidinedione 97.00%
5G
$ 2100.00

AccelPharmtech
(3S)-3-amino-2,6-Piperidinedione 97.00%
1G
$ 1600.00

Total 8 raw suppliers

Chemical Property of 2,6-Piperidinedione, 3-amino-, (3S)-

Chemical Property:

Boiling Point:334.5±35.0 °C(Predicted)
PKA:11.15±0.40(Predicted)
PSA：75.68000
Density:1.243±0.06 g/cm3(Predicted)
LogP:-0.27350
XLogP3:-1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:128.058577502
Heavy Atom Count:9
Complexity:155

Purity/Quality:

97% ^*data from raw suppliers

(S)-3-Amino-piperidine-2,6-dione 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC(=O)C1N
Isomeric SMILES:C1CC(=O)NC(=O)[C@H]1N

Technology Process of 2,6-Piperidinedione, 3-amino-, (3S)-

There total 6 articles about 2,6-Piperidinedione, 3-amino-, (3S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 22785-43-9,179915-11-8
(S)-benzyl (2,6-dioxopiperidin-3-yl)carbamate

: 29883-25-8,673485-72-8
(S)-3-aminopiperidine-2,6-dione

Guidance literature:: With hydrogen; 5% palladium over charcoal; In ethanol; for 1h;

Reference yield:

: 2650-64-8
Cbz-L-Gln

: 29883-25-8,673485-72-8
(S)-3-aminopiperidine-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide; tetrahydrofuran / -78 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C

With 1-hydroxy-pyrrolidine-2,5-dione; palladium 10% on activated carbon; hydrogen; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1039/c3cc00178d