Propanedinitrile, 2-[[4-(difluoromethoxy)phenyl]methylene]-

Base Information

Chemical Name:Propanedinitrile, 2-[[4-(difluoromethoxy)phenyl]methylene]-
CAS No.:304685-68-5
Molecular Formula:C₁₁H₆F₂N₂O
Molecular Weight:220.178
Hs Code.:
DSSTox Substance ID:DTXSID701200644
Mol file:304685-68-5.mol

Synonyms:304685-68-5;Propanedinitrile, 2-[[4-(difluoromethoxy)phenyl]methylene]-;2-{[4-(difluoromethoxy)phenyl]methylidene}propanedinitrile;DTXSID701200644;HMS1755E16;2-(4-Difluoromethoxybenzylidene)-;MCK100018;STL358456;AKOS001063148;CS-0304973;2-(4-(Difluoromethoxy)benzylidene)malononitrile;[4-(difluoromethoxy)benzylidene]propanedinitrile;Z44300036;2-[[4-(Difluoromethoxy)phenyl]methylene]propanedinitrile

Suppliers and Price of Propanedinitrile, 2-[[4-(difluoromethoxy)phenyl]methylene]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanedinitrile, 2-[[4-(difluoromethoxy)phenyl]methylene]-

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:220.04481914
Heavy Atom Count:16
Complexity:335

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C=C(C#N)C#N)OC(F)F

Technology Process of Propanedinitrile, 2-[[4-(difluoromethoxy)phenyl]methylene]-

There total 1 articles about Propanedinitrile, 2-[[4-(difluoromethoxy)phenyl]methylene]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73960-07-3
4-difluoromethoxybenzaldehyde

: 109-77-3
malononitrile

: 304685-68-5
2-(4-difluoromethoxybenzylidene)malononitrile

Guidance literature:: With piperidine; In ethanol; for 1h; Heating;
DOI:10.1021/jm049597+

Reference yield:

: 304685-68-5
2-(4-difluoromethoxybenzylidene)malononitrile

: 791619-88-0
2-amino-4-(4-difluoromethoxyphenyl)-6-mercaptopyridine-3,5-dicarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / ethanol / 4 h / Heating

2: Na₂S / dimethylformamide / 2 h / 80 °C

With sodium sulfide; triethylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm049597+

Reference yield:

: 304685-68-5
2-(4-difluoromethoxybenzylidene)malononitrile

: LUF₅₈₂₆

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / ethanol / 4 h / Heating

2: Na₂S / dimethylformamide / 2 h / 80 °C

3: 44 percent / NaHCO₃ / dimethylformamide / 2 h / 20 °C

With sodium sulfide; sodium hydrogencarbonate; triethylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm049597+