Bicyclo[1.1.0]butane-1-carboxylic acid

Base Information

Chemical Name:Bicyclo[1.1.0]butane-1-carboxylic acid
CAS No.:30493-99-3
Molecular Formula:C5H6O2
Molecular Weight:98.09990
Hs Code.:2916209090
DSSTox Substance ID:DTXSID30603962
Nikkaji Number:J88.669F
Wikidata:Q82501598
Mol file:30493-99-3.mol

Synonyms:Bicyclo[1.1.0]butane-1-carboxylic acid;30493-99-3;Bicyclo[1.1.0]butane-2-carboxylic Acid;2384545-99-5;DTXSID30603962;MFCD19160711;AKOS006240292;AT31011;PB24438;Bicyclo[1.1.0]butane-1-carboxylicacid;SY298042;EN300-245855

Suppliers and Price of Bicyclo[1.1.0]butane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Bicyclo[1.1.0]butane-1-carboxylic acid

Chemical Property:

PSA：37.30000
LogP:0.48100
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:98.036779430
Heavy Atom Count:7
Complexity:133

Purity/Quality:: 98+% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2C1(C2)C(=O)O

Technology Process of Bicyclo[1.1.0]butane-1-carboxylic acid

There total 2 articles about Bicyclo[1.1.0]butane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 15963-46-9,177498-41-8,177498-42-9
3-chlorocyclobutanecarboxylic acid methyl ester

: 30493-99-3
Bicyclo<1,1,0>butan-1-carboxylsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: NaH, 2,5-di-tert-butyl-<1,4>benzoquinone / tetrahydrofuran

2: aq. NaOH, 2,5-di-tert-butyl-<1,4>benzoquinone, phenothiazine

With sodium hydroxide; 10H-phenothiazine; 2,5-di-tert-butyl-p-benzoquinone; sodium hydride; In tetrahydrofuran;
DOI:10.1021/ja00730a022