4-Cyclohexyl-4-[(1H-1,2,4-triazol-1-yl)methyl]piperidine

Base Information

Chemical Name:4-Cyclohexyl-4-[(1H-1,2,4-triazol-1-yl)methyl]piperidine
CAS No.:312638-92-9
Molecular Formula:C14H24N4
Molecular Weight:248.371
Hs Code.:
DSSTox Substance ID:DTXSID00514495
Wikidata:Q82374856
Mol file:312638-92-9.mol

Synonyms:312638-92-9;4-Cyclohexyl-4-[(1H-1,2,4-triazol-1-yl)methyl]piperidine;SCHEMBL3143700;DTXSID00514495;BDAJCEHKRPQTJD-UHFFFAOYSA-N;FT-0752656;4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidine;4-cyclohexyl-4-[1,2,4]triazol-1-ylmethylpiperidine;4-cyclohexyl-4-[1,2,4]triazole-1-ylmethylpiperidine

Suppliers and Price of 4-Cyclohexyl-4-[(1H-1,2,4-triazol-1-yl)methyl]piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Cyclohexyl-4-[(1H-1,2,4-triazol-1-yl)methyl]piperidine

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:248.20009678
Heavy Atom Count:18
Complexity:257

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)C2(CCNCC2)CN3C=NC=N3

Technology Process of 4-Cyclohexyl-4-[(1H-1,2,4-triazol-1-yl)methyl]piperidine

There total 8 articles about 4-Cyclohexyl-4-[(1H-1,2,4-triazol-1-yl)methyl]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 312638-87-2
4-cyclohexyl-4-hydroxymethylpiperidine-1-carboxylic acid tert-butyl ester

: 312638-92-9
4-cyclohexyl-4-(1H-1,2,4-triazol-1-yl-methyl)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂

2: dimethylformamide

3: HCl / CH₂Cl₂

With hydrogenchloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm025539h

Reference yield:

: 4220-08-0
(4-phenyl-piperidin-4-yl)-methanol

: 312638-92-9
4-cyclohexyl-4-(1H-1,2,4-triazol-1-yl-methyl)piperidine

Guidance literature:: Multi-step reaction with 5 steps

1: H₂; HCl / Rh/Al₂O₃ / methanol

2: Et₃N / methanol

3: Et₃N / CH₂Cl₂

4: dimethylformamide

5: HCl / CH₂Cl₂

With hydrogenchloride; hydrogen; triethylamine; Rh/Al₂O₃; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm025539h

Reference yield:

: 77-17-8
Normeperidine

: 312638-92-9
4-cyclohexyl-4-(1H-1,2,4-triazol-1-yl-methyl)piperidine

Guidance literature:: Multi-step reaction with 6 steps

1: LAH / tetrahydrofuran

2: H₂; HCl / Rh/Al₂O₃ / methanol

3: Et₃N / methanol

4: Et₃N / CH₂Cl₂

5: dimethylformamide

6: HCl / CH₂Cl₂

With hydrogenchloride; lithium aluminium tetrahydride; hydrogen; triethylamine; Rh/Al₂O₃; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm025539h