1-Acetyl-1H-indole-3-carbaldehyde

Base Information

Chemical Name:1-Acetyl-1H-indole-3-carbaldehyde
CAS No.:22948-94-3
Molecular Formula:C11H9NO2
Molecular Weight:187.198
Hs Code.:29339990
European Community (EC) Number:245-347-0
NSC Number:61289
UNII:56ESZ895CE
DSSTox Substance ID:DTXSID60177489
Nikkaji Number:J307.765I
Wikidata:Q72435301
Metabolomics Workbench ID:123890
ChEMBL ID:CHEMBL1650260
Mol file:22948-94-3.mol

Synonyms:22948-94-3;1-Acetyl-1H-indole-3-carbaldehyde;N-Acetylindole-3-carboxaldehyde;1-Acetyl-3-indolecarboxaldehyde;1-acetylindole-3-carbaldehyde;1-Acetylindole-3-carboxaldehyde;1H-Indole-3-carboxaldehyde, 1-acetyl-;56ESZ895CE;EINECS 245-347-0;1-Acetyl-1H-indole-3-carboxaldehyde;MFCD00039691;NSC-61289;1-acetyl-3-formylindole;NSC61289;OpticalBrightenerVBL;N-acetylindole-3-aldehyde;UNII-56ESZ895CE;SCHEMBL870631;N-Acetylindol-3-carboxaldehyde;CHEMBL1650260;DTXSID60177489;CHEBI:133207;BCP26459;NSC 61289;STK386919;AKOS001588414;1-Acetyl-3-indolecarboxaldehyde, 98%;N-ACETYL-3-INDOLECARBOXALDEHYDE;PS-5825;NCGC00186378-01;SY061794;INDOLE-3-CARBOXALDEHYDE, 1-ACETYL-;CS-0142077;FT-0607280;A-1400

Suppliers and Price of 1-Acetyl-1H-indole-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Acetyl-1H-indole-3-carbaldehyde
2.5g
$ 75.00

SynQuest Laboratories
1-Acetyl-1H-indole-3-carboxaldehyde
1 g
$ 16.00

SynQuest Laboratories
1-Acetyl-1H-indole-3-carboxaldehyde
5 g
$ 34.00

SynQuest Laboratories
1-Acetyl-1H-indole-3-carboxaldehyde
25 g
$ 136.00

Sigma-Aldrich
1-Acetyl-3-indolecarboxaldehyde 98%
5g
$ 55.10

Matrix Scientific
1-Acetyl-1H-indole-3-carbaldehyde
25g
$ 118.00

Matrix Scientific
1-Acetyl-1H-indole-3-carbaldehyde
5g
$ 28.00

Frontier Specialty Chemicals
N-Acetyl-3-indolecarboxaldehyde 98%
1g
$ 18.00

Frontier Specialty Chemicals
N-Acetyl-3-indolecarboxaldehyde 98%
5g
$ 61.00

Crysdot
1-Acetyl-1H-indole-3-carbaldehyde 97%
100g
$ 303.00

Total 76 raw suppliers

Chemical Property of 1-Acetyl-1H-indole-3-carbaldehyde

Chemical Property:

Appearance/Colour:Light yellow crystals
Vapor Pressure:0.000116mmHg at 25°C
Melting Point:165 °C(lit.)
Refractive Index:1.598
Boiling Point:336 °C at 760 mmHg
Flash Point:157 °C
PSA：39.07000
Density:1.19 g/cm³
LogP:2.11390
Storage Temp.:2-8°C
Sensitive.:Air Sensitive
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:187.063328530
Heavy Atom Count:14
Complexity:252

Purity/Quality:

99% ^*data from raw suppliers

1-Acetyl-1H-indole-3-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)N1C=C(C2=CC=CC=C21)C=O
Uses Reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-cultureReactant for preparation of homoallylic amines as antimicrobial agentsReactant for preparation of pyrrole-based hydrazones as potential tuberculostaticsReactant for synthesis of neoechinulin A and derivativesReactant for synthesis of substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agentsReactant for preparation of RNA-specific live cell imaging probes E36, E144 and F22

Technology Process of 1-Acetyl-1H-indole-3-carbaldehyde

There total 9 articles about 1-Acetyl-1H-indole-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 75-36-5
acetyl chloride

: 22948-94-3
1-acetyl-3-indolylcarbaldehyde

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; Heating;

Reference yield: 99.0%

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 108-24-7
acetic anhydride

: 22948-94-3
1-acetyl-3-indolylcarbaldehyde

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.orglett.1c01134

Reference yield: 87.0%

: 99842-79-2
1-(3-(hydroxymethyl)-1H-indol-1-yl)ethanone

: 22948-94-3
1-acetyl-3-indolylcarbaldehyde

Guidance literature:: With Iron(III) nitrate nonahydrate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; sodium chloride; In 1,2-dichloro-ethane; at 20 ℃; for 1.5h;
DOI:10.1039/c3ob40226f