Benzene, 1-[(bromomethyl)sulfinyl]-4-methyl-, (S)-

Base Information

• Chemical Name: Benzene, 1-[(bromomethyl)sulfinyl]-4-methyl-, (S)-
• CAS No.: 31350-96-6
• Molecular Formula: C8H9BrOS
• Molecular Weight: 233.129
• Mol file: 31350-96-6.mol

Synonyms:

Chemical Property of Benzene, 1-[(bromomethyl)sulfinyl]-4-methyl-, (S)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-[(bromomethyl)sulfinyl]-4-methyl-, (S)-

There total 2 articles about Benzene, 1-[(bromomethyl)sulfinyl]-4-methyl-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

(R)-methyl p-tolyl sulfoxide (1519-39-7) → (S)-1-(bromomethylsulfinyl)-4-methylbenzene (31350-96-6)

Guidance literature:

(R)-methyl p-tolyl sulfoxide; With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 0 ℃;

With bromine; In tetrahydrofuran; at -78 ℃; for 0.0833333h;

DOI:10.1021/jo0487552

Reference yield:

(R)-(+)-methyl p-tolyl sulfoxide (1519-39-7) → (+)-bromomethyl p-tolyl sulfoxide (26910-35-0,31350-95-5,31350-96-6,108508-73-2)

Guidance literature:

With pyridine; N-Bromosuccinimide; bromine; In dichloromethane;

DOI:10.1246/bcsj.45.2794

Reference yield: 99.0%

n-Octylamine (111-86-4) + carbon monoxide (201230-82-2) + (S)-1-(bromomethylsulfinyl)-4-methylbenzene (31350-96-6) → (R)-2-(p-tolylsulfinyl)-N-octylacetamide (1403584-67-7)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; cesium fluoride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; under 760.051 Torr;

DOI:10.1021/jo301778n DOI:10.1021/jo301778n

upstream raw materials:

(R)-(+)-methyl p-tolyl sulfoxide

(R)-methyl p-tolyl sulfoxide

Downstream raw materials:

(+)-Methylthiomethyl-p-tolylsulfoxid

(+)-Ethoxymethyl-p-tolylsulfoxid

(+)-(S)-4-Methylphenyl 4-methylphenylthiomethyl sulfoxide

(R)-methyl p-tolyl sulfoxide