6-Methyl-5-Methoxy indole

Base Information

• Chemical Name: 6-Methyl-5-Methoxy indole
• CAS No.: 3139-10-4
• Molecular Formula: C10H11NO
• Molecular Weight: 161.20000
• Hs Code.: 2933990090
• Mol file: 3139-10-4.mol

Synonyms:5-methoxy-6-methylindole;1H-Indole,5-methoxy-6-methyl;5-Methoxy-6-methyl-indol;QC-2978;6-Methyl-5-methoxy indole;RD-0150;

Chemical Property of 6-Methyl-5-Methoxy indole

Chemical Property:

• PSA: 25.02000
• LogP: 2.48490
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99%min ^*data from raw suppliers

5-methoxy-6-methyl-1H-indole 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Methyl-5-Methoxy indole

There total 3 articles about 6-Methyl-5-Methoxy indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Methoxy-2-methyl-4-nitro-5-vinyl-benzene → 5-methoxy-6-methylindole (3139-10-4)

Guidance literature:

With iron; acetic acid; In ethanol; for 0.5h; Heating;

DOI:10.1021/jm00185a014

Reference yield:

1-methoxy-2,5-dimethyl-4-nitrobenzene (3139-06-8) → 5-methoxy-6-methylindole (3139-10-4)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide / 96 h / 130 - 150 °C

2: 0.25 g / glacial CH₃COOH, Fe / ethanol / 0.5 h / Heating

With iron; acetic acid; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00185a014

Reference yield:

→ 5-methoxy-6-methylindole (3139-10-4)

Guidance literature:

5-Methoxy-6-methyl-indol-2-carbonsaeure b. 300grad;

upstream raw materials:

1-methoxy-2,5-dimethyl-4-nitrobenzene

Refernces

• 1、 Glennon, R. A.,Schubert, E.,Jacyno, J. M.,Rosecrans, J. A.. "Studies on Several 7-Substituted N,N-Dimethyltryptamines". . p. 1222 - 1226. Retrieved 2007/10/02.