3-(2-Piperidylmethyl)indole

Base Information

Chemical Name:3-(2-Piperidylmethyl)indole
CAS No.:5275-05-8
Molecular Formula:C14H18N2
Molecular Weight:214.3061
Hs Code.:
DSSTox Substance ID:DTXSID00967200
Nikkaji Number:J62.687B
Mol file:5275-05-8.mol

Synonyms:3-(2-Piperidylmethyl)indole;5275-05-8;3-[(Piperidin-2-yl)methyl]-1H-indole;INDOLE, 3-(2-PIPERIDYLMETHYL)-;3-(2-piperidinylmethyl)indole;SCHEMBL8790419;DTXSID00967200;NQAIQKCDQAOHIA-UHFFFAOYSA-N;3-(2-Piperidylmethyl)-1H-indole;3-(2-Piperidinylmethyl)-1H-indole;3-(piperid-2-ylmethyl)-1H-indole;LS-83354;EN300-1838226

Suppliers and Price of 3-(2-Piperidylmethyl)indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-(2-Piperidylmethyl)indole

Chemical Property:

Vapor Pressure:3.09E-06mmHg at 25°C
Boiling Point:388.3°C at 760 mmHg
Flash Point:188.7°C
Density:1.109g/cm³
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:214.146998583
Heavy Atom Count:16
Complexity:229

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCNC(C1)CC2=CNC3=CC=CC=C32

Technology Process of 3-(2-Piperidylmethyl)indole

There total 7 articles about 3-(2-Piperidylmethyl)indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 51626-59-6
(1H-indol-3-yl)(pyridin-2-yl)methanol

: 5275-05-8
3-indolyl-2'-piperidylmethane

Guidance literature:: With sodium; butan-1-ol; for 0.5h; Heating;
DOI:10.1021/ja00342a045

Reference yield:

: 5275-05-8
3-indolyl-2'-piperidylmethane

Guidance literature:: With ethanol; acetic acid; platinum; Hydrogenation;
DOI:10.1021/ja01578a027

Reference yield:

: 1121-60-4
pyridine-2-carbaldehyde

: 5275-05-8
3-indolyl-2'-piperidylmethane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) ethylmagnesium bromide / 1.) diethyl ether, -50 deg C (20 min) , room temperature (1 h), 2.) diethyl ether, CH₂Cl₂, -30 deg C, 4 h

2: 43 percent / Na, butanol / 0.5 h / Heating

With ethylmagnesium bromide; sodium; butan-1-ol;
DOI:10.1021/ja00342a045