1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazole-4-carbaldehyde

Base Information

Chemical Name:1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazole-4-carbaldehyde
CAS No.:318233-98-6
Molecular Formula:C₁₈H₁₆N₂OS
Molecular Weight:308.404
Hs Code.:
DSSTox Substance ID:DTXSID101151007
Mol file:318233-98-6.mol

Synonyms:1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazole-4-carbaldehyde;318233-98-6;SCHEMBL6782113;DTXSID101151007;1-methyl-5-(4-methylphenyl)sulfanyl-3-phenylpyrazole-4-carbaldehyde;MFCD00244903;AKOS005088226;3K-347S;1-Methyl-5-[(4-methylphenyl)thio]-3-phenyl-1H-pyrazole-4-carboxaldehyde

Suppliers and Price of 1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazole-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazole-4-carbaldehyde

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:308.09833431
Heavy Atom Count:22
Complexity:364

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)SC2=C(C(=NN2C)C3=CC=CC=C3)C=O

Technology Process of 1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazole-4-carbaldehyde

There total 3 articles about 1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazole-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 883-38-5
5-chloro-1-methyl-3-phenyl-1H-pyrazole-4-carboxaldehyde

: 106-45-6
para-thiocresol

: 318233-98-6
1-methyl-3-phenyl-5-p-tolylsulfanyl-1H-pyrazole-4-carbaldehyde

Guidance literature:: With triethylamine; In dimethyl sulfoxide; at 40 ℃; for 12h;
DOI:10.1016/j.bmcl.2006.12.020

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 318233-98-6
1-methyl-3-phenyl-5-p-tolylsulfanyl-1H-pyrazole-4-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: H₂SO₄ / ethanol / 17 h / Heating

2: POCl₃ / 12 h / 80 °C

3: Et₃N / dimethylsulfoxide / 12 h / 40 °C

With sulfuric acid; triethylamine; trichlorophosphate; In ethanol; dimethyl sulfoxide;
DOI:10.1016/j.bmcl.2006.12.020

Reference yield:

: 34347-81-4
1-methyl-3-phenyl-5-hydroxyl-1H-pyrazol

: 318233-98-6
1-methyl-3-phenyl-5-p-tolylsulfanyl-1H-pyrazole-4-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃ / 12 h / 80 °C

2: Et₃N / dimethylsulfoxide / 12 h / 40 °C

With triethylamine; trichlorophosphate; In dimethyl sulfoxide;
DOI:10.1016/j.bmcl.2006.12.020