ethyl 2-(ethylamino)acetate

Base Information

• Chemical Name: ethyl 2-(ethylamino)acetate
• CAS No.: 3183-20-8
• Molecular Formula: C6H13NO2
• Molecular Weight: 131.175
• Hs Code.: 2922499990
• Mol file: 3183-20-8.mol

Synonyms:ethyl N-ethyl-4-aminobenzoate;ethyl N-ethyl-glycinate;ethyl ethyl-aminoacetate;ethyl 2-ethylaminoacetate;4-ethylamino-benzoic acid ethyl ester;4-Aethylamino-benzoesaeure-aethylester;EtNHCH2COOEt;ethyl 4-ethylaminobenzoate;Benzoic acid,4-(ethylamino)-,ethyl ester;ethyl 4-(N-ethylamino)benzoate;N-ethylglycine ethyl ester;

Chemical Property of ethyl 2-(ethylamino)acetate

Chemical Property:

• Boiling Point: 158.2±23.0 °C(Predicted)
• PKA: 7.88±0.10(Predicted)
• PSA: 38.33000
• Density: 0.937±0.06 g/cm3(Predicted)
• LogP: 0.54990

Purity/Quality:

98%Min ^*data from raw suppliers

Ethylamino-aceticacidethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 2-(ethylamino)acetate

There total 1 articles about ethyl 2-(ethylamino)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl N,N-diethylglycinate (2644-21-5) → ethyl N-ethyl-glycinate (3183-20-8) + acetaldehyde (75-07-0,9002-91-9)

Guidance literature:

With rhodium(III) 5,10,15,20-tetra(p-sulfonatophenyl)porphyrin; oxygen; trifluoroacetic acid; In ethanol; at 100 ℃; for 2h; under 760.051 Torr;

DOI:10.1039/c2cc37263k

Reference yield: 99.0%

trans-1,2-cyclohexanbicarboxylic anhydride + ethyl N-ethyl-glycinate (3183-20-8) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → Trans-2[[N-[2-(hydroxyamino)-2-oxoethyl]-N-ethylamino]carbonyl]--cyclohexanecarboxylic acid

Guidance literature:

With hydrogenchloride; sodium hydroxide; sodium chloride; hydroxylamine hydrochloride; In methanol; dichloromethane; chloroform; water;

Reference yield: 99.0%

ethyl N-ethyl-glycinate (3183-20-8) + (+/-)-trans-1,2-cyclohexanedicarboxylic anhydride (14166-21-3) → trans-2-<<(2-ethoxy-2-oxoethyl)ethylamino>carbonyl>cyclohexanecarboxylic acid

Guidance literature:

With triethylamine; In dichloromethane; for 20h; Ambient temperature;

DOI:10.1021/jm00058a006

upstream raw materials:

ethyl N,N-diethylglycinate

Downstream raw materials:

1-ethyl-2-amino-1,5-dihydro-imidazol-4-one

Refernces