3-Pyridinecarboxylic acid, 2,5-dimethyl-, ethyl ester

Base Information

Chemical Name:3-Pyridinecarboxylic acid, 2,5-dimethyl-, ethyl ester
CAS No.:31931-53-0
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:

Synonyms:2,5-dimethyl-3-ethoxycarbonyl-pyridine;2,5-DIMETHYL-NICOTINIC ACID ETHYL ESTER;ETHYL 2,5-DIMETHYLNICOTINATE;2,5-Dimethyl-nicotinsaeure-aethylester;

Suppliers and Price of 3-Pyridinecarboxylic acid, 2,5-dimethyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Pyridinecarboxylic acid, 2,5-dimethyl-, ethyl ester

Chemical Property:

PSA：39.19000
LogP:1.87510

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Pyridinecarboxylic acid, 2,5-dimethyl-, ethyl ester

There total 1 articles about 3-Pyridinecarboxylic acid, 2,5-dimethyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1721-26-2
ethyl 2-methyl nicotinate

: 20859-02-3
L-tert-Leucine

: 31931-53-0
3-(ethoxycarbonyl)-2,5-dimethylpyridine

: 545394-60-3
ethyl 6-(tert-butyl)-2-methylnicotinate

Guidance literature:: ethyl 2-methyl nicotinate; L-tert-Leucine; With ammonium peroxydisulfate; water; trifluoroacetic acid; In 1,2-dichloro-ethane; at 23 ℃; for 0.0166667h;

With silver nitrate; In 1,2-dichloro-ethane; at 80 ℃; for 24h;
DOI:10.1021/acs.orglett.6b01754

Reference yield: 63.0%

: 31931-53-0
3-(ethoxycarbonyl)-2,5-dimethylpyridine

: 124796-97-0
ethyl 2-(chloromethyl)-5-methylnicotinate

Guidance literature:: With trichloroisocyanuric acid; In dichloromethane; at 20 ℃; for 16h;

Reference yield:

: 31931-53-0
3-(ethoxycarbonyl)-2,5-dimethylpyridine

: 695-98-7
2,3,5-trimethyl-pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: lithium alanate; diethyl ether / und anschliessendes Erwaermen_.

2: thionyl chloride

3: palladium/charcoal; methanol / Hydrogenation

With methanol; palladium on activated charcoal; lithium aluminium tetrahydride; thionyl chloride; diethyl ether;