1,4-Diphenylbutan-1-amine hydrochloride

Base Information

Chemical Name:1,4-Diphenylbutan-1-amine hydrochloride
CAS No.:74533-88-3
Molecular Formula:C₁₆H₁₉N
Molecular Weight:225.334
Hs Code.:2921499090
European Community (EC) Number:854-183-4
DSSTox Substance ID:DTXSID70585834
Mol file:74533-88-3.mol

Synonyms:1,4-diphenylbutan-1-amine hydrochloride;74533-88-3;101286-41-3;1,4-diphenylbutan-1-amine;hydrochloride;DTXSID70585834;BEA28641;AKOS027378699;SB81978;CS-0234958;EN300-15063;G39114;1,4-Diphenylbutan-1-amine--hydrogen chloride (1/1);Z115458460

Suppliers and Price of 1,4-Diphenylbutan-1-amine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,4-DIPHENYLBUTAN-1-AMINE HYDROCHLORIDE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
1,4-DIPHENYLBUTAN-1-AMINE HYDROCHLORIDE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
1,4-DIPHENYLBUTAN-1-AMINE HYDROCHLORIDE 95.00%
1G
$ 852.55

Total 3 raw suppliers

Chemical Property of 1,4-Diphenylbutan-1-amine hydrochloride

Chemical Property:

Vapor Pressure:1.59E-05mmHg at 25°C
Boiling Point:365.2°C at 760 mmHg
Flash Point:173.4°C
PSA：26.02000
LogP:5.21160
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:261.1284273
Heavy Atom Count:18
Complexity:190

Purity/Quality:

99% ^*data from raw suppliers

1,4-DIPHENYLBUTAN-1-AMINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCCC(C2=CC=CC=C2)N.Cl

Technology Process of 1,4-Diphenylbutan-1-amine hydrochloride

There total 7 articles about 1,4-Diphenylbutan-1-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 300-57-2,57807-91-7
allylbenzene

: 14856-79-2
N-benzyl(trimethylsilyl)amine

: 74533-88-3
1,4-diphenylbutan-1-amine

: 2-methyl-1,3-diphenylpropan-1-amine

: 2-methyl-1,3-diphenylpropan-1-amine

Guidance literature:: allylbenzene; N-benzyl(trimethylsilyl)amine; With tetrakis(dimethylamido)zirconium (IV); In benzene-d6; at 145 ℃; for 72h; Inert atmosphere; Glovebox; Sealed tube;

With water; sodium hydroxide; In methanol; dichloromethane; benzene-d6; Overall yield = 82 percent; Overall yield = 92 mg; regioselective reaction;
DOI:10.1021/jacs.9b10465

Reference yield:

: 100-46-9
benzylamine

: 74533-88-3
1,4-diphenylbutan-1-amine

: 2-methyl-1,3-diphenylpropan-1-amine

: 2-methyl-1,3-diphenylpropan-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexane / 0.08 h / 0 °C / Inert atmosphere; Schlenk technique

1.2: 0 - 20 °C / Inert atmosphere; Schlenk technique

2.1: tetrakis(dimethylamido)zirconium (IV) / benzene-d6 / 72 h / 145 °C / Inert atmosphere; Glovebox; Sealed tube

With tetrakis(dimethylamido)zirconium (IV); n-butyllithium; In diethyl ether; hexane; benzene-d6;
DOI:10.1021/jacs.9b10465